1094614-84-2

1094614-84-2 structure
1094614-84-2 structure
  • Name: BIX 02188
  • Chemical Name: bix-02188
  • CAS Number: 1094614-84-2
  • Molecular Formula: C25H24N4O2
  • Molecular Weight: 412.48
  • Catalog: Biochemical Inhibitor Mitogen-activated protein kinase (MAPK) MEK inhibitor
  • Create Date: 2018-12-28 10:02:51
  • Modify Date: 2025-08-23 17:42:00
  • (E/Z)-BIX02188 is a MEK5/ERK5 pathway inhibitor. (E/Z)-BIX02188 inhibits the catalytic function of purified MEK5 enzyme.(E/Z)-BIX02188 can be used for the role of MEK5/ERK5 pathway in various biological systems [1].

Name bix-02188
Synonyms (3Z)-3-[({3-[(Dimethylamino)methyl]phenyl}amino)(phenyl)methylene]-2-oxo-6-indolinecarboxamide
1H-Indole-6-carboxamide, 3-[[[3-[(dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-2-oxo-, (3Z)-
3-[[[3-[(Dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-2-oxo-1H-indole-6-carboxamide
bix02188
Description (E/Z)-BIX02188 is a MEK5/ERK5 pathway inhibitor. (E/Z)-BIX02188 inhibits the catalytic function of purified MEK5 enzyme.(E/Z)-BIX02188 can be used for the role of MEK5/ERK5 pathway in various biological systems [1].
Related Catalog
References

[1]. Tatake RJ, et al. Identification of pharmacological inhibitors of the MEK5/ERK5 pathway. Biochem Biophys Res Commun. 2008 Dec 5;377(1):120-5.  

Density 1.3±0.1 g/cm3
Boiling Point 615.8±55.0 °C at 760 mmHg
Molecular Formula C25H24N4O2
Molecular Weight 412.48
Flash Point 326.2±31.5 °C
Exact Mass 412.189911
PSA 87.46000
LogP 2.36
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.688
Hazard Codes Xi
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