G 28UCM
Modify Date: 2025-08-25 16:24:54
G 28UCM structure
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Common Name | G 28UCM | ||
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| CAS Number | 1094451-90-7 | Molecular Weight | 464.378 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 895.1±65.0 °C at 760 mmHg | |
| Molecular Formula | C24H16O10 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 313.3±27.8 °C | |
Use of G 28UCMUCM05 (G28UCM) is a potent inhibitor of fatty acid synthase (FASN) shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines[1]. UCM05 is a Filamentous temperature-sensitive protein Z (FtsZ) inhibitor and inhibits the growth of the Gram-positive bacterium B. subtilis with MIC values of 100 μM but lack activity on the Gram-negative bacterium E. coli[2]. |
| Name | 1,3-Naphthalenediyl bis(3,4,5-trihydroxybenzoate) |
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| Synonym | More Synonyms |
| Description | UCM05 (G28UCM) is a potent inhibitor of fatty acid synthase (FASN) shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines[1]. UCM05 is a Filamentous temperature-sensitive protein Z (FtsZ) inhibitor and inhibits the growth of the Gram-positive bacterium B. subtilis with MIC values of 100 μM but lack activity on the Gram-negative bacterium E. coli[2]. |
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| Related Catalog | |
| References |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 895.1±65.0 °C at 760 mmHg |
| Molecular Formula | C24H16O10 |
| Molecular Weight | 464.378 |
| Flash Point | 313.3±27.8 °C |
| Exact Mass | 464.074341 |
| LogP | 4.63 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.787 |
| InChIKey | KJCWIWDPTNVWRX-UHFFFAOYSA-N |
| SMILES | O=C(Oc1cc(OC(=O)c2cc(O)c(O)c(O)c2)c2ccccc2c1)c1cc(O)c(O)c(O)c1 |
| Storage condition | -20°C |
| 1,3-Naphthalenediyl bis(3,4,5-trihydroxybenzoate) |
| Benzoic acid, 3,4,5-trihydroxy-, 1,3-naphthalenediyl ester |