111844-21-4
111844-21-4 structure
- Name: G-{d-Arg}-GDSP
- Chemical Name: G-{d-Arg}-GDSP
- CAS Number: 111844-21-4
- Molecular Formula: C22H37N9O10
- Molecular Weight: 587.58
- Catalog: Research Areas Others
- Create Date: 2022-11-21 13:55:54
- Modify Date: 2024-04-06 13:22:46
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G-{d-Arg}-GDSP is an RGD peptide analogue that binds to the adhesion receptor of integrins and inhibits cellular fibronectin attachment as well as osteoclast resorption[1].
| Name | G-{d-Arg}-GDSP |
|---|
| Description | G-{d-Arg}-GDSP is an RGD peptide analogue that binds to the adhesion receptor of integrins and inhibits cellular fibronectin attachment as well as osteoclast resorption[1]. |
|---|---|
| Related Catalog | |
| In Vitro | G-{d-Arg}-GDSP (17-850 μM, 10 days) significantly inhibits osteoclastic resorption at 170 μM in 17-day-old fetal mouse metacarpals and inhibits 45Ca release in osteoclast precursor-dependent bone organ culture[1]. G-{d-Arg}-GDSP (170 μM, 4 days) shows inhibition of anchorage of periosteal TRAP+ precursors to the mineralized matrix and subsequent osteoclast formation compared with the control group[1]. |
| Molecular Formula | C22H37N9O10 |
|---|---|
| Molecular Weight | 587.58 |