GRL-0496
Modify Date: 2025-08-25 14:42:14
GRL-0496 structure
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Common Name | GRL-0496 | ||
|---|---|---|---|---|
| CAS Number | 1087243-14-8 | Molecular Weight | 272.69 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H9ClN2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GRL-0496GRL-0496 is a potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitor, with an IC50 of 30 nM in both enzyme inhibitory and antiviral assays. GRL-0496 shows SARS-CoV antiviral activity, with an EC50 of 6.9 μM[1]. |
| Name | GRL-0496 |
|---|
| Description | GRL-0496 is a potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitor, with an IC50 of 30 nM in both enzyme inhibitory and antiviral assays. GRL-0496 shows SARS-CoV antiviral activity, with an EC50 of 6.9 μM[1]. |
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| Related Catalog | |
| Target |
IC50: 30 nM (SARS-CoV 3CLpro)[1] |
| In Vitro | GRL-0496 shows the best SARS-CoV antiviral activity, with an EC EC50 of 6.9 μM[1]. |
| References |
| Molecular Formula | C14H9ClN2O2 |
|---|---|
| Molecular Weight | 272.69 |