2,5-Biphenyldiol

Modify Date: 2024-01-04 12:18:29

2,5-Biphenyldiol structure	Common Name	2,5-Biphenyldiol
	CAS Number	1079-21-6	Molecular Weight	186.207
	Density	1.2±0.1 g/cm3	Boiling Point	383.0±30.0 °C at 760 mmHg
	Molecular Formula	C₁₂H₁₀O₂	Melting Point	98-100 °C(lit.)
	MSDS	Chinese USA	Flash Point	192.3±19.2 °C
	Symbol	GHS07	Signal Word	Warning

Use of 2,5-Biphenyldiol

TFIIH Modulator-12 is a small molecule destabilization inducer of the trichothiodystrophy group A protein (TTD-A or p8) dimerization which modulates TFIIH transcriptional activity.

Name	Phenylhydroquinone
Synonym	More Synonyms

Density	1.2±0.1 g/cm3
Boiling Point	383.0±30.0 °C at 760 mmHg
Melting Point	98-100 °C(lit.)
Molecular Formula	C₁₂H₁₀O₂
Molecular Weight	186.207
Flash Point	192.3±19.2 °C
Exact Mass	186.068085
PSA	40.46000
LogP	2.09
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.640

2,5-Biphenyldiol MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DV4550000

CHEMICAL NAME :: 2,5-Biphenyldiol

CAS REGISTRY NUMBER :: 1079-21-6

BEILSTEIN REFERENCE NO. :: 1949429

LAST UPDATED :: 199806

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C12-H10-O2

MOLECULAR WEIGHT :: 186.22

WISWESSER LINE NOTATION :: QR DQ BR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1010 mg/m3/4H

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - acute pulmonary edema Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 22 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 mg/m3/6H/2W-I

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - dyspnea Endocrine - changes in spleen weight Endocrine - changes in thymus weight

TYPE OF TEST :: DNA adduct

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 100 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 259,1,1991

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	DV4550000
HS Code	2907299090

HS Code	2907299090
Summary	2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%

Cytotoxic effects of phenyl-hydroquinone and some hydroquinones on isolated rat hepatocytes.

Biochem. Pharmacol. 44(6) , 1059-65, (1992)

The cytotoxic effects of phenyl-hydroquinone (PHQ) and some other hydroquinones on freshly isolated rat hepatocytes were investigated. Addition of PHQ (0.5 or 0.75 mM) to the hepatocytes elicited dose...

Tuning surface hydrophilicity/hydrophobicity of hydrocarbon proton exchange membranes (PEMs).

J. Colloid. Interface Sci. 466 , 168-77, (2016)

The effect of annealing on the surface hydrophilicity of various representative classes of hydrocarbon-based proton exchange membranes (PEMs) is investigated. In all cases, a more hydrophilic membrane...

Metabolism of phenylhydroquinone by prostaglandin (H) synthase: possible implications in o-phenylphenol carcinogenesis.

Carcinogenesis 12(1) , 145-9, (1991)

o-Phenylphenol (OPP) and its sodium salt sodium ortho-phenylphenate (NaOPP) are broad spectrum fungicides and antibacterial agents. Both are urinary bladder and renal carcinogens in the Fischer 344 ra...

2,5-Dihydroxy-biphenyl

2,5-Biphenyldiol

EINECS 214-091-1

[1,1'-Biphenyl]-2,5-diol

4-hydroxy-2-phenylphenol

Biphenyl-2,5-diol

2-phenylhydroquinone

PHENYLHYDROQUINONE

MFCD00002342

2,5-Dihydroxybiphenyl

2,5-Dihydroxybiphenyl,2,5-Biphenyldiol

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 2,5-Biphenyldiol
Price: ￥628.0/5g ￥1618.0/25g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: TFIIH Modulator12
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-Phenylhydroquinone
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Price: ￥468/25g

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2,5-Biphenyldiol

Use of 2,5-Biphenyldiol

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MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

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