mTOR inhibitor WYE-28

Modify Date: 2024-01-11 22:10:41

mTOR inhibitor WYE-28 structure	Common Name	mTOR inhibitor WYE-28
	CAS Number	1062172-60-4	Molecular Weight	586.64
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₀H₃₄N₈O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of mTOR inhibitor WYE-28

mTOR inhibitor WYE-28 (compound 28) is a selective inhibitor of mTOR>/b< (IC50)=0.08 nM. mTOR inhibitor WYE-28 inhibits PI3Kα with an IC50 value of 6 nM. mTOR inhibitor WYE-28 shows a metabolic time (T1/2) in nude mouse microsomes of 13 min[1].

Name	mTOR inhibitor WYE-28

Description	mTOR inhibitor WYE-28 (compound 28) is a selective inhibitor of mTOR>/b< (IC50)=0.08 nM. mTOR inhibitor WYE-28 inhibits PI3Kα with an IC50 value of 6 nM. mTOR inhibitor WYE-28 shows a metabolic time (T1/2) in nude mouse microsomes of 13 min[1].
Related Catalog	Signaling Pathways >> PI3K/Akt/mTOR >> mTOR Research Areas >> Cancer
References	[1]. Zask A, et al. ATP-competitive inhibitors of the mammalian target of rapamycin: design and synthesis of highly potent and selective pyrazolopyrimidines. J Med Chem. 2009 Aug 27;52(16):5013-6.

Molecular Formula	C₃₀H₃₄N₈O₅
Molecular Weight	586.64
InChIKey	DLIGFKRUAOAIBA-UHFFFAOYSA-N
SMILES	COC(=O)N1CCC(n2ncc3c(N4CCOCC4)nc(-c4ccc(NC(=O)Nc5ccc(CO)cc5)cc4)nc32)CC1

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mTOR inhibitor WYE-28

Use of mTOR inhibitor WYE-28

Names

mTOR inhibitor WYE-28 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.