Dopamine D2 receptor antagonist-1

Modify Date: 2025-08-27 18:37:07

Dopamine D2 receptor antagonist-1 structure	Common Name	Dopamine D2 receptor antagonist-1
	CAS Number	1055411-77-2	Molecular Weight	259.37
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₁₇N₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Dopamine D2 receptor antagonist-1

Dopamine D2 receptor antagonist-1 is a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R) with sub-mM affinity[1].

Name	Dopamine D2 receptor antagonist-1

Description	Dopamine D2 receptor antagonist-1 is a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R) with sub-mM affinity[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease
Target	D2R[1]
References	[1]. Fyfe TJ, et al. Subtle modifications to a thieno[2,3-d]pyrimidine scaffold yield negative allosteric modulators and agonists of the dopamine D2 receptor. Eur J Med Chem. 2019 Apr 15;168:474-490.

Molecular Formula	C₁₄H₁₇N₃S
Molecular Weight	259.37

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