1055411-77-2

1055411-77-2 structure

1055411-77-2 structure

Name: Dopamine D2 receptor antagonist-1
Chemical Name: Dopamine D2 receptor antagonist-1
CAS Number: 1055411-77-2
Molecular Formula: C₁₄H₁₇N₃S
Molecular Weight: 259.37
Catalog: Signaling Pathways GPCR/G Protein Dopamine Receptor
Create Date: 2020-01-23 20:13:51
Modify Date: 2024-01-12 09:18:40
Dopamine D2 receptor antagonist-1 is a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R) with sub-mM affinity[1].

Name	Dopamine D2 receptor antagonist-1

Description	Dopamine D2 receptor antagonist-1 is a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R) with sub-mM affinity[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease
Target	D2R[1]
References	[1]. Fyfe TJ, et al. Subtle modifications to a thieno[2,3-d]pyrimidine scaffold yield negative allosteric modulators and agonists of the dopamine D2 receptor. Eur J Med Chem. 2019 Apr 15;168:474-490.

Molecular Formula	C₁₄H₁₇N₃S
Molecular Weight	259.37