α,β-Methylene-ATP dilithium

Modify Date: 2024-04-05 12:10:51

α,β-Methylene-ATP dilithium Structure
α,β-Methylene-ATP dilithium structure
Common Name α,β-Methylene-ATP dilithium
CAS Number 104809-20-3 Molecular Weight 519.09
Density N/A Boiling Point N/A
Molecular Formula C11H18Li2N5O12P3 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of α,β-Methylene-ATP dilithium


α,β-Methylene ATP dilithium, a phosphonic analog of ATP, is a P2X3 and P2X7 receptor ligand[1]. α,β-Methylene ATP dilithium is a highly selective agonist for P2X1 and P2X3, with practically no activity at P2X2,4-7[2].

 Names

Name α,β-Methyleneadenosine 5′-triphosphate lithium salt
Synonym More Synonyms

 α,β-Methylene-ATP dilithium Biological Activity

Description α,β-Methylene ATP dilithium, a phosphonic analog of ATP, is a P2X3 and P2X7 receptor ligand[1]. α,β-Methylene ATP dilithium is a highly selective agonist for P2X1 and P2X3, with practically no activity at P2X2,4-7[2].
Related Catalog
References

[1]. Arribas-Blázquez M, et al. Overexpression of P2X3 and P2X7 Receptors and TRPV1 Channels in Adrenomedullary Chromaffin Cells in a Rat Model of Neuropathic Pain. Int J Mol Sci. 2019 Jan 3;20(1).

[2]. Claudio Coddou, et al. Activation and regulation of purinergic P2X receptor channels. Pharmacol Rev. 2011 Sep;63(3):641-83

 Chemical & Physical Properties

Molecular Formula C11H18Li2N5O12P3
Molecular Weight 519.09
Exact Mass 511.02500
PSA 302.16000
Storage condition 20°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases 22-26-36
RIDADR NONH for all modes of transport

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 Synonyms

lithium,[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]methyl-hydroxyphosphoryl] hydrogen phosphate