Eslicarbazepine

Modify Date: 2025-08-21 08:12:57

Eslicarbazepine Structure
Eslicarbazepine structure
Common Name Eslicarbazepine
CAS Number 104746-04-5 Molecular Weight 254.284
Density 1.3±0.1 g/cm3 Boiling Point 431.3±55.0 °C at 760 mmHg
Molecular Formula C15H14N2O2 Melting Point 188-190°C
MSDS N/A Flash Point 214.6±31.5 °C

 Use of Eslicarbazepine


Eslicarbazepine is an oral anticonvulsant indicated for the adjunctive treatment of partial seizures.

 Names

Name Eslicarbazepine
Synonym More Synonyms

 Eslicarbazepine Biological Activity

Description Eslicarbazepine is an oral anticonvulsant indicated for the adjunctive treatment of partial seizures.
Related Catalog
In Vivo Eslicarbazepine is an anti-epileptic drug, chemically related to carbamazepine but with a more favorable safety profile. Eslicarbazepine acetate is a prodrug for eslicarbazepine (S-licarbazepine), which is a dual a dual Inhibitor of β-Secretase and voltage-gated sodium channel[1][2].
References

[1]. Finelli E, et al. Patch testing in a case of eslicarbazepine and carbamazepine induced cutaneous reaction. Eur Ann Allergy Clin Immunol. 2018 Sep;50(5):229-231.

[2]. Sibhghatulla Shaikh, et al. Aptiom (Eslicarbazepine Acetate) as a Dual Inhibitor of β-Secretase and Voltage-Gated Sodium Channel: Advancement in Alzheimer's Disease-Epilepsy Linkage via an Enzoinformatics Study. CNS & Neurological Disorders Drug Targets Volume 13 , Issue 7 , 2014.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 431.3±55.0 °C at 760 mmHg
Melting Point 188-190°C
Molecular Formula C15H14N2O2
Molecular Weight 254.284
Flash Point 214.6±31.5 °C
Exact Mass 254.105530
PSA 66.56000
LogP 0.93
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.677
Storage condition 2-8℃

 Safety Information

HS Code 2933990090

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

(+)-Licarbazepine
(S)-(+)-10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
(S)-(+)-licarbazepine
5H-Dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-10-hydroxy-, (10S)-
T C676 BN&T&J BVZ IQ &&S Form
MHD
(S)-10-hydroxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide
Eslicarbazepine
5-hydroxy-4a,5-dihydro-4H-dibenzo[b,f]azepine-10-carboxamide
(10S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide
S-licarbazepine
(S)-Licarbazepine
S5VXA428R4
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