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104746-04-5

104746-04-5 structure
104746-04-5 structure
  • Name: Eslicarbazepine
  • Chemical Name: Eslicarbazepine
  • CAS Number: 104746-04-5
  • Molecular Formula: C15H14N2O2
  • Molecular Weight: 254.284
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2018-06-19 00:24:06
  • Modify Date: 2024-01-02 19:16:38
  • Eslicarbazepine is an oral anticonvulsant indicated for the adjunctive treatment of partial seizures.
Name Eslicarbazepine
Synonyms (+)-Licarbazepine
(S)-(+)-10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
(S)-(+)-licarbazepine
5H-Dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-10-hydroxy-, (10S)-
T C676 BN&T&J BVZ IQ &&S Form
MHD
(S)-10-hydroxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide
Eslicarbazepine
5-hydroxy-4a,5-dihydro-4H-dibenzo[b,f]azepine-10-carboxamide
(10S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide
S-licarbazepine
(S)-Licarbazepine
S5VXA428R4
Description Eslicarbazepine is an oral anticonvulsant indicated for the adjunctive treatment of partial seizures.
Related Catalog
In Vivo Eslicarbazepine is an anti-epileptic drug, chemically related to carbamazepine but with a more favorable safety profile. Eslicarbazepine acetate is a prodrug for eslicarbazepine (S-licarbazepine), which is a dual a dual Inhibitor of β-Secretase and voltage-gated sodium channel[1][2].
References

[1]. Finelli E, et al. Patch testing in a case of eslicarbazepine and carbamazepine induced cutaneous reaction. Eur Ann Allergy Clin Immunol. 2018 Sep;50(5):229-231.

[2]. Sibhghatulla Shaikh, et al. Aptiom (Eslicarbazepine Acetate) as a Dual Inhibitor of β-Secretase and Voltage-Gated Sodium Channel: Advancement in Alzheimer's Disease-Epilepsy Linkage via an Enzoinformatics Study. CNS & Neurological Disorders Drug Targets Volume 13 , Issue 7 , 2014.
Density 1.3±0.1 g/cm3
Boiling Point 431.3±55.0 °C at 760 mmHg
Melting Point 188-190°C
Molecular Formula C15H14N2O2
Molecular Weight 254.284
Flash Point 214.6±31.5 °C
Exact Mass 254.105530
PSA 66.56000
LogP 0.93
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.677
Storage condition 2-8℃
HS Code 2933990090
HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Chemsrc provides CAS#:104746-04-5 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 104746-04-5 | Chemsrc address: https://www.chemsrc.com/en/baike/452910.html

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