Sumatriptan hydrochloride

Modify Date: 2024-01-02 15:50:08

Sumatriptan hydrochloride structure	Common Name	Sumatriptan hydrochloride
	CAS Number	103628-62-2	Molecular Weight	331.86
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₂₂ClN₃O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Sumatriptan hydrochloride

Sumatriptan (GR 43175) hydrochloride is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan hydrochloride can be used for migraine headache research[1][2].

Name	Sumatriptan hydrochloride

Description	Sumatriptan (GR 43175) hydrochloride is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan hydrochloride can be used for migraine headache research[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Target	5-HT1D Receptor:17 nM (Ki) 5-HT1B Receptor:27 nM (Ki) 5-HT1A Receptor:100 nM (Ki)
References	[1]. S J Peroutka, et al. Sumatriptan (GR 43175) interacts selectively with 5-HT1B and 5-HT1D binding sites. Eur J Pharmacol. 1989 Apr 12;163(1):133-6. [2]. K L Dechant, et al. Sumatriptan. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the acute treatment of migraine and cluster headache. Drugs. 1992 May;43(5):776-98.

Molecular Formula	C₁₄H₂₂ClN₃O₂S
Molecular Weight	331.86

Sumatriptan hydrochloride

Use of Sumatriptan hydrochloride

Names

Sumatriptan hydrochloride Biological Activity

Chemical & Physical Properties