Levamlodipine

Modify Date: 2024-01-02 17:47:28

Levamlodipine Structure
Levamlodipine structure
 Common Name Levamlodipine
CAS Number 103129-82-4 Molecular Weight 567.051
Density 1.2±0.1 g/cm3 Boiling Point 527.2±50.0 °C at 760 mmHg
Molecular Formula C20H25ClN2O5 Melting Point 102-104°C
MSDS N/A Flash Point 272.6±30.1 °C

 Use of Levamlodipine


Levamlodipine ((S)-Amlodipine) is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina[1].

 Names

Name (S)-Amlodipine
Synonym More Synonyms

 Levamlodipine Biological Activity

Description Levamlodipine ((S)-Amlodipine) is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina[1].
Related Catalog
Target

Calcium channel[1].
References

[1]. Jain R, et al. Polyaniline-graphene oxide nanocomposite sensor for quantification of calcium channel blocker levamlodipine. Mater Sci Eng C Mater Biol Appl. 2016 Aug 1;65:205-14.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 527.2±50.0 °C at 760 mmHg
Melting Point 102-104°C
Molecular Formula C20H25ClN2O5
Molecular Weight 567.051
Flash Point 272.6±30.1 °C
Exact Mass 566.148987
PSA 99.88000
LogP 4.16
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.546
Storage condition -20°C Freezer

 Safety Information

Hazard Codes Xi

 Synthetic Route

Amlodipine structure

Amlodipine

CAS#:88150-42-9

~%

Levamlodipine Structure

Levamlodipine

CAS#:103129-82-4
Literature: WO2008/51056 A1, ; Page/Page column 5; 7; 8 ;
2-[(2-azidoethoxy)methyl]-4(S)-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-1,4-dihydropyridine structure

2-[(2-azidoetho...

CAS#:125711-60-6

~%

Levamlodipine Structure

Levamlodipine

CAS#:103129-82-4
Literature: Journal of Medicinal Chemistry, , vol. 29, # 9 p. 1696 - 1702
N/A structure

N/A

CAS#:143191-87-1

~64%

Levamlodipine Structure

Levamlodipine

CAS#:103129-82-4
Literature: Goldmann; Stoltefuss; Born Journal of Medicinal Chemistry, 1992 , vol. 35, # 18 p. 3341 - 3344
2-(2-azidoethoxy)methyl-3-carboxy-4-(2-chlorophenyl)-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine structure

2-(2-azidoethox...

CAS#:103069-49-4

~%

Levamlodipine Structure

Levamlodipine

CAS#:103129-82-4
Literature: Journal of Medicinal Chemistry, , vol. 29, # 9 p. 1696 - 1702
N/A structure

N/A

CAS#:103094-34-4

~%

Levamlodipine Structure

Levamlodipine

CAS#:103129-82-4
Literature: Journal of Medicinal Chemistry, , vol. 29, # 9 p. 1696 - 1702
N/A structure

N/A

CAS#:103069-47-2

~%

Levamlodipine Structure

Levamlodipine

CAS#:103129-82-4
Literature: Journal of Medicinal Chemistry, , vol. 29, # 9 p. 1696 - 1702
N/A structure

N/A

CAS#:103069-48-3

~%

Levamlodipine Structure

Levamlodipine

CAS#:103129-82-4
Literature: Journal of Medicinal Chemistry, , vol. 29, # 9 p. 1696 - 1702
Amlodipine structure

Amlodipine

CAS#:88150-42-9

~%

d-Amlodipine structure

d-Amlodipine

CAS#:103129-81-3
Levamlodipine Structure

Levamlodipine

CAS#:103129-82-4
Literature: WO2010/148191 A2, ; Page/Page column 45-49; 59 ;
2-((2-((tert-butoxycarbonyl)amino)ethoxy)-methyl)-4-(2-chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridine structure

2-((2-((tert-bu...

CAS#:143290-24-8

~%

Levamlodipine Structure

Levamlodipine

CAS#:103129-82-4
Literature: Journal of Medicinal Chemistry, , vol. 35, # 18 p. 3341 - 3344

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

Norvasc
3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (4S)-, benzenesulfonate (1:1)
l-Amlodipine
Levamlodipine Besylate Tablets
LevoaMlodipine
3,5-Pyridinedicarboxylic acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
T6M DHJ B1O2Z CVO2 DR BG& EVO1 F1
2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl Ester
Lodien
UNII:1J444QC288
3-Ethyl 5-methyl 2-{[(2-aminoethyl)oxy]methyl}-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
Levamlodipine
3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
3-Ethyl 5-methyl (4S)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylate benzenesulfonate (1:1)
Amlodipine
Levoamlodipine Besylate
3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylate
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Related Compounds: More...
Levamlodipine-d4
1346616-97-4
Levamlodipine-d4
1346617-19-3
Levamlodipine malate
736178-83-9
Levamlodipine besylate
150566-71-5
Chemsrc provides Levamlodipine(CAS#:103129-82-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Levamlodipine are included as well.>> amp version: Levamlodipine

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