N-(2-Hydroxyethyl)piperazine

Modify Date: 2024-01-01 19:50:40

N-(2-Hydroxyethyl)piperazine Structure
N-(2-Hydroxyethyl)piperazine structure
Common Name N-(2-Hydroxyethyl)piperazine
CAS Number 103-76-4 Molecular Weight 130.19
Density 1.0±0.1 g/cm3 Boiling Point 245.0±20.0 °C at 760 mmHg
Molecular Formula C6H14N2O Melting Point -38.5 °C
MSDS Chinese USA Flash Point 101.9±21.8 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of N-(2-Hydroxyethyl)piperazine


1-(2-Hydroxyethyl)piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name N-(2-Hydroxyethyl)piperazine
Synonym More Synonyms

 N-(2-Hydroxyethyl)piperazine Biological Activity

Description 1-(2-Hydroxyethyl)piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
In Vitro 1-Piperazineethanol 是一种羟烷基取代的哌嗪,用于制备药物化合物。它还用作制造聚氨酯催化剂、腐蚀抑制剂、表面活性剂、合成纤维、药物的中间体。也用于合成三亚乙基二胺。

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 245.0±20.0 °C at 760 mmHg
Melting Point -38.5 °C
Molecular Formula C6H14N2O
Molecular Weight 130.19
Flash Point 101.9±21.8 °C
Exact Mass 130.110611
PSA 35.50000
LogP -0.45
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.475
Water Solubility MISCIBLE

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TL6825000
CHEMICAL NAME :
1-Piperazineethanol
CAS REGISTRY NUMBER :
103-76-4
BEILSTEIN REFERENCE NO. :
0104361
LAST UPDATED :
199710
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C6-H14-N2-O
MOLECULAR WEIGHT :
130.22
WISWESSER LINE NOTATION :
T6M DNTJ D2Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/6/1970
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,865,1986 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4920 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
3350 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Behavioral - muscle contraction or spasticity
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 45(5),67,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>5 mL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/6/1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
3720 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Behavioral - muscle contraction or spasticity
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 45(5),67,1980

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant
Risk Phrases R38;R41
Safety Phrases S26-S36/39-S37/39
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS TL6825000
HS Code 2933599090

 Synthetic Route

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

1-(2-Hydroxyethyl)piperazine
T6M DNTJ D2Q
N-(2-Hydroxyethyl)Piperazine
1-Piperazinethanol
2-Piperazin-1-ylethanol
N-(β-Hydroxyethyl)piperazine
4-(2-hydroxyethyl)-piperazine
EINECS 203-142-3
PIPERAZINE ETHANOL
2-(piperazin-1-yl)ethanol
Piperazinoethanol
MFCD00005970
2-(1-piperazinyl)-1-ethanol
usafdo-22
N-(2-hydroxy-ethyl)-piperazine
1-Piperazineethanol
2-(1-Piperazinyl)ethanol
(β-Hydroxyethyl)piperazine
1-(β-Hydroxyethyl)piperazine
N-(2-HYDROXYETHYL) PIPERAZINE
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