Moracin P

Modify Date: 2025-08-20 19:26:13

Moracin P structure	Common Name	Moracin P
	CAS Number	102841-46-3	Molecular Weight	326.343
	Density	1.4±0.1 g/cm3	Boiling Point	560.6±50.0 °C at 760 mmHg
	Molecular Formula	C₁₉H₁₈O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	292.8±30.1 °C

Use of Moracin P

Moracin P is a 2-arylbenzofuran isolated from the Mori Cortex Radicis. Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin P reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin P has neuroprotective and anti-inflammatory effects[1][2][3].

Name	5-(6-hydroxy-7,7-dimethyl-3a,4,5,6-tetrahydrofuro[3,2-g]chromen-2-yl)benzene-1,3-diol
Synonym	More Synonyms

Description	Moracin P is a 2-arylbenzofuran isolated from the Mori Cortex Radicis. Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin P reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin P has neuroprotective and anti-inflammatory effects[1][2][3].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> HIF/HIF Prolyl-Hydroxylase Research Areas >> Neurological Disease
In Vitro	Moracin P enhances cell viability in dose-dependent manner against oxygen-glucose deprivation (OGD)-induced cell death in neuroblastoma SH-SY5Y cells with an EC50 value of 10.4 μM. Moracin P reduces ROS production in OGD-induced cell death (IC50 values of 1.9 μM). Consequently, reactive oxygen species (ROS) are overexpressed in OGD-induced cells and Moracin P reduces ROS induced by OGD in dosedependent manner[1].
References	[1]. Hak Ju Lee, et al. Inhibitory effect of 2-arylbenzofurans from the Mori Cortex Radicis (Moraceae) on oxygen glucose deprivation (OGD)-induced cell death of SH-SY5Y cells. Arch Pharm Res. 2011 Aug;34(8):1373-80. [2]. Yan Xia, et al. HIF-1α inhibitors: synthesis and biological evaluation of novel moracin O and P analogues. Eur J Med Chem. 2011 Jun;46(6):2386-96. [3]. Besse Hardianti, et al. Anti-inflammatory compounds moracin O and P from Morus alba Linn. (Sohakuhi) target the NF‑κB pathway. Mol Med Rep. 2020 Dec;22(6):5385-5391.

Density	1.4±0.1 g/cm3
Boiling Point	560.6±50.0 °C at 760 mmHg
Molecular Formula	C₁₉H₁₈O₅
Molecular Weight	326.343
Flash Point	292.8±30.1 °C
Exact Mass	326.115417
PSA	83.06000
LogP	3.19
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.662
InChIKey	QFUCSEIKNTUPPA-GOSISDBHSA-N
SMILES	CC1(C)Oc2cc3oc(-c4cc(O)cc(O)c4)cc3cc2CC1O

Hazard Codes	Xi

5-(6-Hydroxy-7,7-dimethyl-6,7-dihydro-5H-furo[3,2-g]chromen-2-yl)-1,3-benzenediol

5-(6-hydroxy-7,7-dimethyl-6,7-dihydro-5H-furo[3,2-g]chromen-2-yl)benzene-1,3-diol

1,3-Benzenediol, 5-(6,7-dihydro-6-hydroxy-7,7-dimethyl-5H-furo[3,2-g][1]benzopyran-2-yl)-

Moracin P

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: MoracinP
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Moracin P
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Moracin P
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.