Urease-IN-10

Modify Date: 2025-08-27 09:27:32

Urease-IN-10 Structure
Urease-IN-10 structure
Common Name Urease-IN-10
CAS Number 1012205-70-7 Molecular Weight 450.34
Density N/A Boiling Point N/A
Molecular Formula C20H17Cl2N3O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Urease-IN-10


Urease-IN-10 (Conjugate 4) is a competitive Urease inhibitor, with an IC50 of 3.59±0.07 μM and a Ki of 7.45 μM. Urease-IN-10 is a conjugate consisting of Diclofenac (HY-15036) and Sulfanilamide (HY-B0242). Diclofenac-sulfanilamide inhibits the Jack bean urease(JBU) in a competitive manner[1].

 Names

Name Urease-IN-10

 Urease-IN-10 Biological Activity

Description Urease-IN-10 (Conjugate 4) is a competitive Urease inhibitor, with an IC50 of 3.59±0.07 μM and a Ki of 7.45 μM. Urease-IN-10 is a conjugate consisting of Diclofenac (HY-15036) and Sulfanilamide (HY-B0242). Diclofenac-sulfanilamide inhibits the Jack bean urease(JBU) in a competitive manner[1].
Related Catalog
References

[1]. Ahmad S, et al. Exploring the Potential of New Benzamide-Acetamide Pharmacophore Containing Sulfonamide as Urease Inhibitors: Structure–Activity Relationship, Kinetics Mechanism, and In Silico Studies. 2023 Nov 22.

 Chemical & Physical Properties

Molecular Formula C20H17Cl2N3O3S
Molecular Weight 450.34
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