1012205-70-7

1012205-70-7 structure

Name: Urease-IN-10
Chemical Name: Urease-IN-10
CAS Number: 1012205-70-7
Molecular Formula: C₂₀H₁₇Cl₂N₃O₃S
Molecular Weight: 450.34
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2024-03-30 15:29:57
Modify Date: 2025-08-27 09:27:32
Urease-IN-10 (Conjugate 4) is a competitive Urease inhibitor, with an IC50 of 3.59±0.07 μM and a Ki of 7.45 μM. Urease-IN-10 is a conjugate consisting of Diclofenac (HY-15036) and Sulfanilamide (HY-B0242). Diclofenac-sulfanilamide inhibits the Jack bean urease(JBU) in a competitive manner[1].

Name	Urease-IN-10

Description	Urease-IN-10 (Conjugate 4) is a competitive Urease inhibitor, with an IC50 of 3.59±0.07 μM and a Ki of 7.45 μM. Urease-IN-10 is a conjugate consisting of Diclofenac (HY-15036) and Sulfanilamide (HY-B0242). Diclofenac-sulfanilamide inhibits the Jack bean urease(JBU) in a competitive manner[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Ahmad S, et al. Exploring the Potential of New Benzamide-Acetamide Pharmacophore Containing Sulfonamide as Urease Inhibitors: Structure–Activity Relationship, Kinetics Mechanism, and In Silico Studies. 2023 Nov 22.

Molecular Formula	C₂₀H₁₇Cl₂N₃O₃S
Molecular Weight	450.34