Urease-IN-10

Names

[ CAS No. ]:
1012205-70-7

[ Name ]:
Urease-IN-10

Biological Activity

[Description]:

Urease-IN-10 (Conjugate 4) is a competitive Urease inhibitor, with an IC50 of 3.59±0.07 μM and a Ki of 7.45 μM. Urease-IN-10 is a conjugate consisting of Diclofenac (HY-15036) and Sulfanilamide (HY-B0242). Diclofenac-sulfanilamide inhibits the Jack bean urease(JBU) in a competitive manner[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Ahmad S, et al. Exploring the Potential of New Benzamide-Acetamide Pharmacophore Containing Sulfonamide as Urease Inhibitors: Structure–Activity Relationship, Kinetics Mechanism, and In Silico Studies. 2023 Nov 22.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H17Cl2N3O3S

[ Molecular Weight ]:
450.34

Related Compounds

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