Amastatin · HCl

Modify Date: 2024-01-02 06:54:15

Amastatin · HCl structure	Common Name	Amastatin · HCl
	CAS Number	100938-10-1	Molecular Weight	511.009
	Density	N/A	Boiling Point	795.1ºC at 760 mmHg
	Molecular Formula	C₂₁H₃₉ClN₄O₈	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	434.7ºC

Use of Amastatin · HCl

Amastatin hydrochloride is a slow, tight binding, competitive aminopeptidase (AP) inhibitor with Ki values of 0.26 nM, 30 nM, 52 nM for Aeromonas aminopeptidase, cytosolic leucine aminopeptidase, microsomal aminopeptidase[1].

Name	Amastatin hydrochloride hydrate
Synonym	More Synonyms

Description	Amastatin hydrochloride is a slow, tight binding, competitive aminopeptidase (AP) inhibitor with Ki values of 0.26 nM, 30 nM, 52 nM for Aeromonas aminopeptidase, cytosolic leucine aminopeptidase, microsomal aminopeptidase[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> Aminopeptidase Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Amastatin hydrochloride (1-10000 ng/ml) exhibitcd inhibitory profiles of E. cuniczcli replication in vitro in a dose dependent manner[2].
References	[1]. S H Wilkes, et al. The Slow, Tight Binding of Bestatin and Amastatin to Aminopeptidases. J Biol Chem. 1985 Oct 25;260(24):13154-62. [2]. J J Millership, et al. In Vitro and in Vivo Evaluation of Aminopeptidase Inhibitors as Antimicrosporidial Therapies. J Eukaryot Microbiol. 2001;Suppl:95S-98S.

Boiling Point	795.1ºC at 760 mmHg
Molecular Formula	C₂₁H₃₉ClN₄O₈
Molecular Weight	511.009
Flash Point	434.7ºC
Exact Mass	510.245636
PSA	208.15000
LogP	1.72140
Vapour Pressure	3.14E-29mmHg at 25°C