Z433927330
Modify Date: 2025-08-25 07:15:14
Z433927330 structure
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Common Name | Z433927330 | ||
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| CAS Number | 1005883-72-6 | Molecular Weight | 364.40 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H20N4O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Z433927330Z433927330 is a potent and selective inhibitor of Aquaporin-7 (AQP7), less potently inhibits AQP3 and AQPs9, with IC50s of ~0.2 µM, ~0.7 µM and ~1.1 µM for mAQP7, mAQP3 and mAQP9, respectively[1]. |
| Name | Z433927330 |
|---|
| Description | Z433927330 is a potent and selective inhibitor of Aquaporin-7 (AQP7), less potently inhibits AQP3 and AQPs9, with IC50s of ~0.2 µM, ~0.7 µM and ~1.1 µM for mAQP7, mAQP3 and mAQP9, respectively[1]. |
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| Related Catalog | |
| Target |
IC50: ~0.2 µM (mAQP7), ~0.7 µM (mAQP3), ~1.1 µM (mAQP9)[1] |
| In Vitro | Z433927330 inhibits glycerol permeability, with an IC50 of ~0.6 µM[1]. |
| References |
| Molecular Formula | C20H20N4O3 |
|---|---|
| Molecular Weight | 364.40 |
| InChIKey | KQUKHINHCUELQL-UHFFFAOYSA-N |
| SMILES | CCOC(=O)c1ccc(NC(=O)NCc2ccc(-n3cccn3)cc2)cc1 |