1005883-72-6
1005883-72-6 structure
- Name: Z433927330
- Chemical Name: Z433927330
- CAS Number: 1005883-72-6
- Molecular Formula: C20H20N4O3
- Molecular Weight: 364.40
- Catalog: Research Areas Others
- Create Date: 2019-06-01 11:02:14
- Modify Date: 2025-08-25 07:15:14
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Z433927330 is a potent and selective inhibitor of Aquaporin-7 (AQP7), less potently inhibits AQP3 and AQPs9, with IC50s of ~0.2 µM, ~0.7 µM and ~1.1 µM for mAQP7, mAQP3 and mAQP9, respectively[1].
| Name | Z433927330 |
|---|
| Description | Z433927330 is a potent and selective inhibitor of Aquaporin-7 (AQP7), less potently inhibits AQP3 and AQPs9, with IC50s of ~0.2 µM, ~0.7 µM and ~1.1 µM for mAQP7, mAQP3 and mAQP9, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: ~0.2 µM (mAQP7), ~0.7 µM (mAQP3), ~1.1 µM (mAQP9)[1] |
| In Vitro | Z433927330 inhibits glycerol permeability, with an IC50 of ~0.6 µM[1]. |
| References |
| Molecular Formula | C20H20N4O3 |
|---|---|
| Molecular Weight | 364.40 |