Potassium tetrachloroplatinate(II)

Modify Date: 2025-08-22 17:37:39

Potassium tetrachloroplatinate(II) structure	Common Name	Potassium tetrachloroplatinate(II)
	CAS Number	10025-99-7	Molecular Weight	415.08700
	Density	3.38 g/mL at 25 °C(lit.)	Boiling Point	N/A
	Molecular Formula	Cl₄K₂Pt	Melting Point	250°C
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS05, GHS06, GHS08	Signal Word	Danger

Name	dipotassium tetrachloroplatinate
Synonym	More Synonyms

Density	3.38 g/mL at 25 °C(lit.)
Melting Point	250°C
Molecular Formula	Cl₄K₂Pt
Molecular Weight	415.08700
Exact Mass	412.76800
LogP	2.75550
Stability	Stable. Incompatible with acids, strong oxidizing agents.
Water Solubility	10 g/L (20 ºC)

Potassium tetrachloroplatinate(II) MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TP1850000

CHEMICAL NAME :: Platinate(2-), tetrachloro-, dipotassium

CAS REGISTRY NUMBER :: 10025-99-7

LAST UPDATED :: 199712

DATA ITEMS CITED :: 34

MOLECULAR FORMULA :: Cl4-Pt.2K

MOLECULAR WEIGHT :: 415.09

WISWESSER LINE NOTATION :: KA2 PT-G4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - child

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Cardiac - other changes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - man

DOSE/DURATION :: 8571 ug/kg

TOXIC EFFECTS :: Gastrointestinal - gastritis Kidney, Ureter, Bladder - renal function tests depressed Blood - eosinophilia

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intradermal

SPECIES OBSERVED :: Human

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Skin and Appendages - primary irritation (after topical exposure) Skin and Appendages - corrosive (after topical exposure)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 45 mg/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 65 umol/L

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 40,1463,1980 *** REVIEWS *** ACGIH TLV-TWA 0.002 mg(Pt)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.002 mg(Pt)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,213,1971 OSHA PEL (Gen Indu):8H TWA 0.002 mg(Pt)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.002 mg(Pt)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.002 mg(Pt)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.002 mg(Pt)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 0.002 mg(Pt)/m3 (dust) JAN 1993 OEL-AUSTRALIA:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-BELGIUM:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-DENMARK:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-FINLAND:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-GERMANY:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-HUNGARY:STEL 0.002 mg(Pt)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-THE PHILIPPINES:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-SWITZERLAND:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

Symbol	GHS05, GHS06, GHS08
Signal Word	Danger
Hazard Statements	H301-H315-H317-H318-H334
Precautionary Statements	P261-P280-P301 + P310-P305 + P351 + P338-P342 + P311
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T:Toxic;
Risk Phrases	R25;R38;R41;R42/43
Safety Phrases	S22-S26-S36/37/39-S45
RIDADR	UN 3288 6.1/PG 3
WGK Germany	1
RTECS	TP1850000
Packaging Group	I; II; III
Hazard Class	6.1
HS Code	2922509090

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N/A

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Precursor 2
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DownStream 8
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HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synthesis of a platinum(II) complex with 2-(4-methoxy-phenyl) imidazo [4,5-f]-[1,10] phenanthrolin and study of its antitumor activity.

Eur. J. Med. Chem. 89 , 77-87, (2014)

A new platinum(II) complex of [Pt(II)(L) (pn)]Cl·2H2O (1) (pn = 1,3-propanediamine) with 2-(4-methoxy-phenyl)imidazo [4,5-f]-[1,10]phenanthrolin (H-L) was synthesized and characterized. In complex 1, ...

Monofunctional Platinum-containing Pyridine-based Ligand Acts Synergistically in Combination with the Phytochemicals Curcumin and Quercetin in Human Ovarian Tumour Models.

Anticancer Res. 35 , 2783-94, (2015)

With the idea that platinum compounds that bind with DNA differently than cisplatin may be better-able to overcome platinum resistance in ovarian tumor, the monofunctional platinum complex tris(imidaz...

Platinum complexes and pyruvate kinase activity.

Gen. Physiol. Biophys. 17(1) , 25-36, (1998)

The interaction of platinum complexes with bovine heart pyruvate kinase (PK) was studied by absorption, CD, fluorescence spectroscopy and enzymic activity test. Our results showed that activity of PK ...

EINECS 233-050-9

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Potassium tetrachloroplatinate(II)

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MFCD00011378

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Potassium tetrachloroplatinate(II)

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Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

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