Landipirdine

Modify Date: 2024-01-06 01:00:34

Landipirdine Structure
Landipirdine structure
Common Name Landipirdine
CAS Number 1000308-25-7 Molecular Weight 362.42
Density 1.3±0.1 g/cm3 Boiling Point 564.7±50.0 °C at 760 mmHg
Molecular Formula C18H19FN2O3S Melting Point N/A
MSDS N/A Flash Point 295.3±30.1 °C

 Use of Landipirdine


Landipirdine is a selective antagonist of 5-HT6R. Landipirdine has great effect on the hERG pharmacophore[1].

 Names

Name Landipirdine
Synonym More Synonyms

 Landipirdine Biological Activity

Description Landipirdine is a selective antagonist of 5-HT6R. Landipirdine has great effect on the hERG pharmacophore[1].
Related Catalog
References

[1]. Harris RN 3rd, et al. Highly potent, non-basic 5-HT6 ligands. Site mutagenesis evidence for a second binding mode at 5-HT6 for antagonism. Bioorg Med Chem Lett. 2010 Jun 1;20(11):3436-40.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 564.7±50.0 °C at 760 mmHg
Molecular Formula C18H19FN2O3S
Molecular Weight 362.42
Flash Point 295.3±30.1 °C
Exact Mass 362.110046
LogP 2.63
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.593

 Synonyms

1-({(1R)-6-[(3-Fluorophenyl)sulfonyl]-1,2,3,4-tetrahydro-1-naphthalenyl}methyl)urea
Landipirdine
UNII:J0NX985GDI
J0NX985GDI
N-{[(1R)-6-(3-fluorobenzenesulfonyl)-1,2,3,4-tetrahydronaphthalen-1- yl]methyl}urea
RO5025181
SYN120
Urea, N-[[(1R)-6-[(3-fluorophenyl)sulfonyl]-1,2,3,4-tetrahydro-1-naphthalenyl]methyl]-
10424
RO5025181-000
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