557-59-5

557-59-5 structure

Name: Lignoceric acid
Chemical Name: lignoceric acid
CAS Number: 557-59-5
Molecular Formula: C₂₄H₄₈O₂
Molecular Weight: 368.637
Catalog: Chemical reagent Organic reagent fatty acid
Create Date: 2018-03-01 08:00:00
Modify Date: 2024-01-03 22:34:55
Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2].

Name	lignoceric acid
Synonyms	Lignoceric acid Tetracosanoic acid EINECS 209-180-7 MFCD00002810 n-tetracosanoic acid

Description	Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2].
Related Catalog	Research Areas >> Neurological Disease
Target	Human Endogenous Metabolite
In Vitro	Heat flux induced by lignoceric acid in HepG2 peroxisomes was exothermic, indicating normal peroxisomal metabolism[1].
References	[1]. Anna Petroni, et al. Thermogenic flux induced by lignoceric acid in peroxisomes isolated from HepG2 cells and from X-adrenoleukodystrophy and control fibroblasts. J Cell Physiol. 2019 Aug;234(10):18344-18348. [2]. J M Bourre, et al. Lignoceric acid biosynthesis in the developing brain. Activities of mitochondrial acetyl-CoA-dependent synthesis and microsomal malonyl-CoA chain-elongating system in relation to myelination. Comparison between normal mouse and dysmyelinating mutants (quaking and jimpy). Eur J Biochem. 1977 Jan 3;72(1):41-7.

Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	36/37/38
Safety Phrases	S26
RIDADR	NONH for all modes of transport
WGK Germany	-