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Related CAS#:

9050-36-6

9050-36-6 structure
9050-36-6 structure
  • Name: Maltodextrin
  • Chemical Name: D-Glucose
  • CAS Number: 9050-36-6
  • Molecular Formula: (C6H10O5)n·xH2O
  • Molecular Weight: 180.156
  • Catalog: Biochemical Carbohydrate Polysaccharide
  • Create Date: 2018-02-04 08:00:00
  • Modify Date: 2024-01-02 11:44:59
  • Maltodextrin, dextrose equivalent 16.5-19.5 can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

Name D-Glucose
Synonyms EINECS 232-940-4
MFCD00146679
Maltodextrin
Description Maltodextrin, dextrose equivalent 16.5-19.5 can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.  

Density 1.6±0.1 g/cm3
Boiling Point 527.1±50.0 °C at 760 mmHg
Melting Point 240ºC (dec.)
Molecular Formula (C6H10O5)n·xH2O
Molecular Weight 180.156
Flash Point 286.7±26.6 °C
Exact Mass 180.063385
PSA 118.22000
LogP -3.17
Vapour Pressure 0.0±3.1 mmHg at 25°C
Index of Refraction 1.573
Storage condition room temp
Water Solubility H2O: 0.1 g/mL hot, complete, yellow to very deep yellow

Section 1. Chemical Product and Company Identification
Maltodextrin
Common Name/
Trade Name
Manufacturer
Commercial Name(s)
Synonym
Chemical Name
Chemical Family
Maltodextrin

Section 4. First Aid Measures
Eye ContactCheck for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for
at least 15 minutes. Cold water may be used. Get medical attention if irritation occurs.
Skin ContactWash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation
develops. Cold water may be used.
Serious Skin ContactNot available.
InhalationIf inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Get medical attention.
Serious InhalationNot available.
IngestionDo NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen
tight clothing such as a collar, tie, belt or waistband.
Serious IngestionNot available.

Section 5. Fire and Explosion Data
Flammability of the Product May be combustible at high temperature.
Auto-Ignition Temperature Not available.
Flash PointsNot available.
Flammable LimitsNot available.
Products of CombustionThese products are carbon oxides (CO, CO2).
Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
Various Substances
Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
of Various SubstancesRisks of explosion of the product in presence of static discharge: Not available.
Fire Fighting MediaSMALL FIRE: Use DRY chemical powder.
and InstructionsLARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks onAs with most organic solids, fire is possible at elevated temperatures Material in powder form, capable of
Fire Hazardscreating a dust explosion.
Special Remarks on Explosion Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential
Hazardsdust explosion hazard.

Section 6. Accidental Release Measures
Small SpillUse appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by
spreading water on the contaminated surface and dispose of according to local and regional authority
requirements.
Large SpillUse a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading
water on the contaminated surface and allow to evacuate through the sanitary system. Be careful that the
product is not present at a concentration level above TLV. Check TLV on the MSDS and with local
authorities.
Maltodextrin

Section 7. Handling and Storage
PrecautionsKeep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not
breathe dust. Keep away from incompatibles such as oxidizing agents.
StorageKeep container tightly closed. Keep container in a cool, well-ventilated area.

Section 8. Exposure Controls/Personal Protection
Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep
exposure to airborne contaminants below the exposure limit.
Personal ProtectionSafety glasses. Lab coat. Dust respirator. Use a dust respirator if ventilation is inadequate or handling of
material creates visible dust clouds, and airborne concentrations exceed the recommended exposure limits.
Be sure to use an approved/certified respirator or equivalent. Gloves.
Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be
a Large Spillused to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a
specialist BEFORE handling this product.
Exposure LimitsFor Particulates Not Otherwise Specified:
TWA: 10 (mg/m3) from ACGIH (TLV) [United States]
TWA: 15 (mg/m3) from OSHA (PEL) [United States]
Consult local authorities for acceptable exposure limits.

Section 9. Physical and Chemical Properties
Physical state and appearance Solid. (Powdered solid. Granular solid.)Odorless.
Odor
TasteNot available.
Molecular WeightNot available.
ColorWhite.
pH (1% soln/water)Not available.
Boiling PointNot available.
Melting Point240°C (464°F)
Critical TemperatureNot available.
Specific GravityNot available.
Vapor PressureNot applicable.
Not available.
Vapor Density
VolatilityNot available.
Odor ThresholdNot available.
Water/Oil Dist. Coeff.Not available.
Ionicity (in Water)Not available.
See solubility in water.
Dispersion Properties
SolubilityEasily soluble in cold water, hot water.

Section 10. Stability and Reactivity Data
StabilityThe product is stable.
Instability TemperatureNot available.
Conditions of InstabilityExcess heat, incompatible materials, dust generation.
Reactive with oxidizing agents.
Incompatibility with various
substances
CorrosivityNon-corrosive in presence of glass.
Maltodextrin
Special Remarks onNot available.
Reactivity
Special Remarks onNot available.
Corrosivity
PolymerizationWill not occur.

Section 11. Toxicological Information
Routes of EntryInhalation. Ingestion.
Toxicity to AnimalsLD50: Not available.
LC50: Not available.
Chronic Effects on Humans Not available.
Other Toxic Effects onSlightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.
Humans
Special Remarks onNot available.
Toxicity to Animals
Special Remarks onNot available.
Chronic Effects on Humans
Special Remarks on otherAcute Potential Health Effects:
Toxic Effects on HumansSkin: Low hazard. May cause skin irritation by mechanical action.
Eyes: Low hazard. Dust may cause eye irritation by mechanical action.
Inhalation: Low hazard. Inhalation of dust may cause respiratory tract irritation by mechanical action.
Ingestion: Expected low hazard.

Section 12. Ecological Information
EcotoxicityNot available.
BOD5 and CODNot available.
Possibly hazardous short term degradation products are not likely. However, long term degradation products
Products of Biodegradation
may arise.
Toxicity of the ProductsThe product itself and its products of degradation are not toxic.
of Biodegradation
Not available.
Special Remarks on the
Products of Biodegradation

Section 13. Disposal Considerations
Waste DisposalWaste must be disposed of in accordance with federal, state and local environmental
control regulations.

Section 14. Transport Information
DOT ClassificationNot a DOT controlled material (United States).
IdentificationNot applicable.
Special Provisions forNot applicable.
Transport
DOT (Pictograms)
Maltodextrin

Section 15. Other Regulatory Information and Pictograms
TSCA 8(b) inventory: Maltodextrin
Federal and State
FDA: Direct Food Additives- GRAS list (21CFR 184)
Regulations
CaliforniaCalifornia prop. 65: This product contains the following ingredients for which the State of California has
Proposition 65found to cause cancer which would require a warning under the statute: No products were found.
Warnings
California prop. 65: This product contains the following ingredients for which the State of California has
found to cause birth defects which would require a warning under the statute: No products were found.
Other RegulationsEINECS: This product is on the European Inventory of Existing Commercial Chemical Substances (EINECS
No. 232-940-4).
Canada: Listed on Canadian Domestic Substance List (DSL).
China: Listed on National Inventory.
Japan: Listed on National Inventory (ENCS).
Korea: Listed on National Inventory (KECI).
Philippines: Listed on National Inventory (PICCS).
Australia: Listed on AICS.
WHMIS (Canada) Not controlled under WHMIS (Canada).
Other Classifications
DSCL (EEC)This product is not classifiedNot applicable.
according to the EU regulations.
Health Hazard
HMIS (U.S.A.)1 National Fire Protection
1 Flammability
1 Association (U.S.A.)
Fire Hazard
1 0 Reactivity
Health
Reactivity
0
Specific hazard
Personal Protection
E
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
TDG (Canada)
(Pictograms)
ADR (Europe)
(Pictograms)
Protective Equipment
Gloves.
Lab coat.
Dust respirator. Be sure to use an
approved/certified respirator or
equivalent.
Maltodextrin


SECTION 16 - ADDITIONAL INFORMATION
N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS HH9450000
HS Code 3505100000
HS Code 3505100000