623114-64-7

623114-64-7 structure

Name: Isopropyl 11-dodecen-1-ylphosphonofluoridate
Chemical Name: Isopropyl dodec-11-enylfluorophosphonate
CAS Number: 623114-64-7
Molecular Formula: C₁₅H₃₀FO₂P
Molecular Weight: 292.370
Catalog: Signaling Pathways GPCR/G Protein Cannabinoid Receptor
Create Date: 2017-04-24 20:23:00
Modify Date: 2024-01-31 17:32:17
Isopropyl dodec-11-enylfluorophosphonate (IDEFP) is an organophosphorus ester that antagonizes the central cannabinoid receptor (CB1) and inhibits FAAH with similar potencies (IC50 = 2 nM)[1].

Name	Isopropyl dodec-11-enylfluorophosphonate
Synonyms	isopropyl di-p-isopropoxyphenylphosphinite Isopropyl 11-dodecen-1-ylphosphonofluoridate Phosphonofluoridic acid, P-11-dodecen-1-yl-, 1-methylethyl ester

Description	Isopropyl dodec-11-enylfluorophosphonate (IDEFP) is an organophosphorus ester that antagonizes the central cannabinoid receptor (CB1) and inhibits FAAH with similar potencies (IC50 = 2 nM)[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> FAAH Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> FAAH Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor
Target	CB1:2 μM (IC50)
References	[1]. Michael A Casasanta, et al. A chemical and biological toolbox for Type Vd secretion: Characterization of the phospholipase A1 autotransporter FplA from Fusobacterium nucleatum. J Biol Chem. 2017 Dec 8;292(49):20240-20254.

3344-70-5

623114-64-7

Literature: Segall, Yoffi; Quistad, Gary B.; Casida, John E. Synthetic Communications, 2003 , vol. 33, # 12 p. 2151 - 2159

99828-63-4

623114-64-7

Literature: Segall, Yoffi; Quistad, Gary B.; Casida, John E. Synthetic Communications, 2003 , vol. 33, # 12 p. 2151 - 2159

210237-15-3

623114-64-7

Literature: Segall, Yoffi; Quistad, Gary B.; Casida, John E. Synthetic Communications, 2003 , vol. 33, # 12 p. 2151 - 2159

623114-62-5

623114-64-7

Literature: Segall, Yoffi; Quistad, Gary B.; Casida, John E. Synthetic Communications, 2003 , vol. 33, # 12 p. 2151 - 2159

67-63-0

623114-63-6

~96%

623114-64-7

Literature: Segall, Yoffi; Quistad, Gary B.; Casida, John E. Synthetic Communications, 2003 , vol. 33, # 12 p. 2151 - 2159