Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-amino-9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-methylsulfanyl-3H-purin-6-one
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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Contact: Ms Wang

2104-66-7

2104-66-7 structure

Name: 2-amino-9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-methylsulfanyl-3H-purin-6-one
Chemical Name: 4-(4-chloroanilino)-4-oxobutanoic acid
CAS Number: 2104-66-7
Molecular Formula: C₁₁H₁₅N₅O₅S
Molecular Weight: 329.33
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2016-12-31 23:32:30
Modify Date: 2024-02-02 01:10:20
8-(Methylthio)guanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

Name	4-(4-chloroanilino)-4-oxobutanoic acid
Synonyms	8-methylsulfanyl-guanosine 8-Methylmercapto-guanosin 8-Methylthioguanosin 8-methylthioguanosine

Description	8-(Methylthio)guanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.

26001-38-7

77-78-1

~63%

2104-66-7

4016-63-1

2104-66-7

Literature: Lin; Cheng; Ishiguro; Sartorelli Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1194 - 1198

Precursor 3
26001-38-7 77-78-1 4016-63-1
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