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52-85-7

52-85-7 structure
52-85-7 structure
  • Name: American Cyanamid 38023
  • Chemical Name: famphur
  • CAS Number: 52-85-7
  • Molecular Formula: C10H16NO5PS2
  • Molecular Weight: 325.341
  • Catalog: analytical chemistry Standard Volatile Organic Compounds (VOCs)
  • Create Date: 2018-06-02 08:00:00
  • Modify Date: 2025-08-27 16:33:00
  • Famphur is an organic thiophosphate and an organothiophosphate insecticide. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an agrochemical, and an anthelminthic drug. Use of famphur as an insecticide is restricted.
Name famphur
Synonyms O-[4-(Dimethylsulfamoyl)phenyl] O,O-dimethyl phosphorothioate
Famofos
American Cyanamid CL 38023
MFCD00055307
Fanfos
Warbex
O-[4-(Dimethylsulfamoyl)phenyl]-O,O-dimethylthiophosphat
O,O-dimethyl-O-(4-dimethylsulfamoylphenyl)phosphorothioate
O-[4-[(dimethylamino)sulfonyl]phenyl] O,O-dimethyl phosphorothioate
4-dimethoxyphosphinothioyloxy-N,N-dimethylbenzenesulfonamide
FAMOPHOS
O-4-dimethylsulfamoylphenyl O,O-dimethyl phosphorothioate
Famphos
Famophos warbex
Dovip
Phosphorothioic Acid O,O-Dimethyl Ester O-Ester with p-Hydroxy-N,N-dimethylbenzenesulfonamide
Thiophosphorsaeure-O,O'-dimethylester-O''-(4-dimethylsulfamoyl-phenylester)
O-{4-[(dimethylamino)sulfonyl]phenyl} O,O-dimethyl thiophosphate
Phosphorothioic acid, O-[4-[(dimethylamino)sulfonyl]phenyl] O,O-dimethyl ester
Famphur
Famfur
EINECS 200-154-0
Thiophosphate de O-[4-(diméthylsulfamoyl)phényle] et de O,O-diméthyle
O,O-Dimethyl-O,p-(dimethylsulfamoyl)phenyl Phosphorothioate
Phosphorothioic Acid O-[4-[(Dimethylamino)sulfonyl]phenyl] O,O-Dimethyl Ester
Warbexol
O.O-Dimethyl-O-p-(dimethylsulfamoyl)-phenylphosphorothioat
American Cyanamid 38023
Density 1.4±0.1 g/cm3
Boiling Point 394.2±52.0 °C at 760 mmHg
Melting Point -96ºC
Molecular Formula C10H16NO5PS2
Molecular Weight 325.341
Flash Point 192.2±30.7 °C
Exact Mass 325.020752
PSA 115.35000
LogP 2.13
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.553

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TF7650000
CHEMICAL NAME :
Phosphorothioic acid, O,O-dimethyl ester, O-ester with p-hydroxy-N,N-dimethylbenzene- sulfonamide
CAS REGISTRY NUMBER :
52-85-7
LAST UPDATED :
199701
DATA ITEMS CITED :
14
MOLECULAR FORMULA :
C10-H16-N-O5-P-S2
MOLECULAR WEIGHT :
325.36
WISWESSER LINE NOTATION :
1OPS&O1&OR DSWN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
28 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 7,299,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 7,299,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
9500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 34,1697,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
11600 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953- Volume(issue)/page/year: 13,366,1965
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1460 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71. Discontinued. Volume(issue)/page/year: 9,119,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - domestic
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JDAH "Organophosphorus Pesticides: Organic and Biological Chemistry," Eto, M., Cleveland, OH, CRC Press, Inc., 1974 Volume(issue)/page/year: -,299,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Mammal - domestic
DOSE/DURATION :
59 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - food intake (animal)
REFERENCE :
VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 54(12),94,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
64 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Behavioral - muscle contraction or spasticity
REFERENCE :
VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 54(12),94,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - wild bird species
DOSE/DURATION :
1800 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 21,315,1972 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
13500 ug/kg/90D-C
TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 50,167,1999 *** REVIEWS *** TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 46,1,1973 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning
Hazard Statements H315-H319-H335-H336-H351-H373
Precautionary Statements P261-P281-P305 + P351 + P338
Target Organs Blood, Central nervous system, Liver
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T
Risk Phrases R63
Safety Phrases 22-24/25-45-36/37-23-53
RIDADR UN 2783
RTECS TF7650000
Packaging Group II
Hazard Class 6.1(a)
HS Code 2935009019
HS Code 2935009019
Summary 2935009019 o-(4-(n,n-dimethylsulfamoyl)phenyl) o,o-dimethyl phosphorothioate。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:35.0%
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