American Cyanamid 38023

Modify Date: 2024-01-11 06:48:21

American Cyanamid 38023 Structure
American Cyanamid 38023 structure
Common Name American Cyanamid 38023
CAS Number 52-85-7 Molecular Weight 325.341
Density 1.4±0.1 g/cm3 Boiling Point 394.2±52.0 °C at 760 mmHg
Molecular Formula C10H16NO5PS2 Melting Point -96ºC
MSDS Chinese USA Flash Point 192.2±30.7 °C
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning

 Use of American Cyanamid 38023


Famphur is an organic thiophosphate and an organothiophosphate insecticide. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an agrochemical, and an anthelminthic drug. Use of famphur as an insecticide is restricted.

 Names

Name famphur
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 394.2±52.0 °C at 760 mmHg
Melting Point -96ºC
Molecular Formula C10H16NO5PS2
Molecular Weight 325.341
Flash Point 192.2±30.7 °C
Exact Mass 325.020752
PSA 115.35000
LogP 2.13
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.553

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TF7650000
CHEMICAL NAME :
Phosphorothioic acid, O,O-dimethyl ester, O-ester with p-hydroxy-N,N-dimethylbenzene- sulfonamide
CAS REGISTRY NUMBER :
52-85-7
LAST UPDATED :
199701
DATA ITEMS CITED :
14
MOLECULAR FORMULA :
C10-H16-N-O5-P-S2
MOLECULAR WEIGHT :
325.36
WISWESSER LINE NOTATION :
1OPS&O1&OR DSWN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
28 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 7,299,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 7,299,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
9500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 34,1697,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
11600 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953- Volume(issue)/page/year: 13,366,1965
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1460 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71. Discontinued. Volume(issue)/page/year: 9,119,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - domestic
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JDAH "Organophosphorus Pesticides: Organic and Biological Chemistry," Eto, M., Cleveland, OH, CRC Press, Inc., 1974 Volume(issue)/page/year: -,299,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Mammal - domestic
DOSE/DURATION :
59 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - food intake (animal)
REFERENCE :
VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 54(12),94,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
64 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Behavioral - muscle contraction or spasticity
REFERENCE :
VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 54(12),94,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - wild bird species
DOSE/DURATION :
1800 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 21,315,1972 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
13500 ug/kg/90D-C
TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 50,167,1999 *** REVIEWS *** TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 46,1,1973 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

 Safety Information

Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning
Hazard Statements H315-H319-H335-H336-H351-H373
Precautionary Statements P261-P281-P305 + P351 + P338
Target Organs Blood, Central nervous system, Liver
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T
Risk Phrases R63
Safety Phrases 22-24/25-45-36/37-23-53
RIDADR UN 2783
RTECS TF7650000
Packaging Group II
Hazard Class 6.1(a)
HS Code 2935009019

 Customs

HS Code 2935009019
Summary 2935009019 o-(4-(n,n-dimethylsulfamoyl)phenyl) o,o-dimethyl phosphorothioate。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:35.0%

 Articles15

More Articles
Development of phage immuno-loop-mediated isothermal amplification assays for organophosphorus pesticides in agro-products.

Anal. Chem. 86(16) , 8441-7, (2014)

Two immuno-loop-mediated isothermal amplification assays (iLAMP) were developed by using a phage-borne peptide that was isolated from a cyclic eight-peptide phage library. One assay was used to screen...

Case histories of bald eagles and other raptors killed by organophosphorus insecticides topically applied to livestock.

J. Wildl. Dis. 23(2) , 292-5, (1987)

Since 1982 when secondary poisoning of a red-tailed hawk (Buteo jamaicensis) was documented following the recommended use of famphur applied topically to cattle, the Patuxent Wildlife Research Center ...

Prediction for the mixture toxicity of six organophosphorus pesticides to the luminescent bacterium Q67.

Ecotoxicol. Environ. Saf. 71(3) , 880-8, (2008)

Organophosphorus (OP) pesticides are ubiquitous in the surface water as mixtures. To examine the mixture toxicity in the multi-component space, the uniform design (UD) which can explore the concentrat...

 Synonyms

O-[4-(Dimethylsulfamoyl)phenyl] O,O-dimethyl phosphorothioate
Famofos
American Cyanamid CL 38023
MFCD00055307
Fanfos
Warbex
O-[4-(Dimethylsulfamoyl)phenyl]-O,O-dimethylthiophosphat
O,O-dimethyl-O-(4-dimethylsulfamoylphenyl)phosphorothioate
O-[4-[(dimethylamino)sulfonyl]phenyl] O,O-dimethyl phosphorothioate
4-dimethoxyphosphinothioyloxy-N,N-dimethylbenzenesulfonamide
FAMOPHOS
O-4-dimethylsulfamoylphenyl O,O-dimethyl phosphorothioate
Famphos
Famophos warbex
Dovip
Phosphorothioic Acid O,O-Dimethyl Ester O-Ester with p-Hydroxy-N,N-dimethylbenzenesulfonamide
Thiophosphorsaeure-O,O'-dimethylester-O''-(4-dimethylsulfamoyl-phenylester)
O-{4-[(dimethylamino)sulfonyl]phenyl} O,O-dimethyl thiophosphate
Phosphorothioic acid, O-[4-[(dimethylamino)sulfonyl]phenyl] O,O-dimethyl ester
Famphur
Famfur
EINECS 200-154-0
Thiophosphate de O-[4-(diméthylsulfamoyl)phényle] et de O,O-diméthyle
O,O-Dimethyl-O,p-(dimethylsulfamoyl)phenyl Phosphorothioate
Phosphorothioic Acid O-[4-[(Dimethylamino)sulfonyl]phenyl] O,O-Dimethyl Ester
Warbexol
O.O-Dimethyl-O-p-(dimethylsulfamoyl)-phenylphosphorothioat
American Cyanamid 38023