| Name | Pinacidil |
|---|---|
| Synonyms |
Pinacidil (hydrate)
Pinacidil . monohydrate 1-Cyano-3-(3,3-dimethylbutan-2-yl)-2-pyridin-4-ylguanidine hydrate (1:1) (+/-)-N-Cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)guanidine MFCD00242745 Hndac GUANIDINE,N-CYANO-N'-4-PYRIDINYL-N''-(1,2,2-TRIMETHYLPROPYL)-, HYDRATE (1:1) Guanidine, N''-cyano-N-4-pyridinyl-N'-(1,2,2-trimethylpropyl)-, hydrate (1:1) Guanidine,N-cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)-,monohydrate Pinacidil monohydrate EINECS 262-294-9 Pinacidil hydrate 1-Cyano-2-(3,3-dimethyl-2-butanyl)-3-(4-pyridinyl)guanidine hydrate (1:1) |
| Description | Pinacidil monohydrate, an antihypertensive drug, is a potassium channel activator. |
|---|---|
| Related Catalog | |
| In Vitro | Pinacidil monohydrate is a potassium channel activator[1]. Pinacidil hydrate is an antihypertensive drug of the class of agents called "potassium channel openers"[2]. Pinacidil hydrate activates the ATP-modulated potassium channels of guinea pog bladder and heart with Ki values of 104 and 251 nM, respectively[3]. |
| References |
| Boiling Point | 356.7ºC at 760 mmHg |
|---|---|
| Melting Point | 164-165ºC |
| Molecular Formula | C13H21N5O |
| Molecular Weight | 263.34 |
| Flash Point | 169.5ºC |
| PSA | 73.10000 |
| LogP | 2.94578 |
| Storage condition | 2-8℃ |
| Water Solubility | ethanol: 14 mg/mL |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R22;R36/37/38 |
| Safety Phrases | S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2933399090 |
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |