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321-30-2

321-30-2 structure
321-30-2 structure
  • Name: Adenine hemisulfate
  • Chemical Name: 1H-Purin-6-amine sulfate
  • CAS Number: 321-30-2
  • Molecular Formula: C5H7N5O4S
  • Molecular Weight: 368.332
  • Catalog: Biochemical Nucleoside drugs Nucleotides and their analogues
  • Create Date: 2018-09-23 17:58:55
  • Modify Date: 2024-01-02 11:08:26
  • Adenine hemisulfate (6-Aminopurine hemisulfate) is a purine derivative with a variety of roles in biochemistry, including cellular respiration, in the form of both the energy-rich adenosine triphosphate (ATP) and the cofactors nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD), and protein synthesis, as a chemical component of DNA and RNA[1][2].

Name 1H-Purin-6-amine sulfate
Synonyms diadenine sulphate
Adenine Sulfate Dihydrate
6-Aminopurine hemisulfate salt
9H-Purin-6-amine sulfate (2:1)
EINECS 206-286-5
Bis(6-amino-9H-purin-1-ium) sulfate
denine,sulfate
Adenine sulfate salt
VITAMIN B SULFATE
Adenine sulfate
7H-Purin-6-amine, sulfate (2:1)
Adenine sulfate,synthetic
ADENINE HEMISULFATE
MFCD00213655
adeniniumsulfate
9H-purin-6-amine, sulfate (2:1)
adenine sulphate
1H-Purin-6-amine sulfate (2:1)
Adenine hemisulfate salt
Adenine sulfate hydrate
6-Aminopurine hemisulfate salt,Adenine sulfate salt
6-Aminopurine Sulfate Dihydrate
7H-Purin-6-amine sulfate
7H-Purin-6-amine sulfate (2:1)
Adenin,Sulfat
Description Adenine hemisulfate (6-Aminopurine hemisulfate) is a purine derivative with a variety of roles in biochemistry, including cellular respiration, in the form of both the energy-rich adenosine triphosphate (ATP) and the cofactors nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD), and protein synthesis, as a chemical component of DNA and RNA[1][2].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Reader V. The assay of vitamin B(4). Biochem J. 1930;24(6):1827-31.

[2]. ORO J, et al. Synthesis of purines under possible primitive earth conditions. I. Adenine from hydrogen cyanide. Arch Biochem Biophys. 1961 Aug;94:217-27.

Boiling Point 553.5ºC at 760mmHg
Melting Point 285 °C (dec.)(lit.)
Molecular Formula C5H7N5O4S
Molecular Weight 368.332
Exact Mass 368.076355
PSA 243.94000
LogP 1.46060
Storage condition Store at RT.
Water Solubility 0.4 g/100 mL

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AU7140000
CAS REGISTRY NUMBER :
321-30-2
LAST UPDATED :
199709
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C5-H5-N5.1/2H2-O4-S
MOLECULAR WEIGHT :
821.71
WISWESSER LINE NOTATION :
T56 BM DN FN HNJ IZ &..H2.S-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 232,302,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Behavioral - ataxia Lungs, Thorax, or Respiration - other changes
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 47,229,1979 *** REVIEWS *** TOXICOLOGY REVIEW ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,24,1957 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83237 No. of Facilities: 59 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 588 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83237 No. of Facilities: 496 (estimated) No. of Industries: 2 No. of Occupations: 8 No. of Employees: 5574 (estimated) No. of Female Employees: 2982 (estimated)
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Precautionary Statements P301 + P312 + P330
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn
Risk Phrases R22
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS AU7140000
HS Code 2933990090
HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%