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514-07-8

514-07-8 structure
514-07-8 structure
  • Name: Taraxerone
  • Chemical Name: Taraxerone
  • CAS Number: 514-07-8
  • Molecular Formula: C30H48O
  • Molecular Weight: 424.702
  • Catalog: Natural product Moss
  • Create Date: 2017-06-11 02:29:47
  • Modify Date: 2024-01-02 19:35:15
  • Taraxerone is isolated from Sedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities with EC50 values of 512.42 and 500.16 μM, respectively[1].
Name Taraxerone
Synonyms 3(2H)-Picenone, 1,4,4a,5,6,6a,8,8a,9,10,11,12,12a,12b,13,14,14a,14b-octadecahydro-4,4,6a,8a,11,11,12b,14b-octamethyl-, (4aR,6aR,8aR,12aR,12bS,14aR,14bR)-
(4aR,6aR,8aR,12aR,12bS,14aR,14bR)-4,4,6a,8a,11,11,12b,14b-Octamethyl-1,4,4a,5,6,6a,8,8a,9,10,11,12,12a,12b,13,14,14a,14b-octadecahydro-3(2H)-picenone
(4aR,6aR,8aR,12aR,12bS,14aR,14bR)-4,4,6a,8a,11,11,12b,14b-octamethyl-1,4,4a,5,6,6a,8,8a,9,10,11,12,12a,12b,13,14,14a,14b-octadecahydropicen-3(2H)-one
Description Taraxerone is isolated from Sedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities with EC50 values of 512.42 and 500.16 μM, respectively[1].
Related Catalog
Target

EC50: 512.42 μM (ADH); 500.16 μM (ALDH)[1]

In Vivo Taraxerone significantly lowers the plasma alcohol and acetaldehyde concentrations in mice. Compare to the control group, the ADH and ALDH expressions in the liver tissues are abruptly increased in the taraxerone-treated groups after ethanol exposure[1]. Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration[1].
References

[1]. Sung CK, et al. Taraxerone enhances alcohol oxidation via increases of alcohol dehyderogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities and gene expressions.Food Chem Toxicol. 2012 Jul;50(7):2508-14.
Density 1.0±0.1 g/cm3
Boiling Point 488.3±44.0 °C at 760 mmHg
Molecular Formula C30H48O
Molecular Weight 424.702
Flash Point 202.8±23.4 °C
Exact Mass 424.370514
PSA 17.07000
LogP 10.48
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.534
Hazard Codes Xi

Chemsrc provides CAS#:514-07-8 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 514-07-8 | Chemsrc address: https://www.chemsrc.com/en/baike/934718.html

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