BioBioPha
China
Product Name: 3-Hydroxy-3-acetonyloxindole
Price: ￥2500.0/5mg
Purity: 95.0%
Stocking Period: 10 Day
Contact: Xueping-Zheng
Email: 1477035482@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2H-Indol-2-one,1,3-dihydro-3-hydroxy-3-(2-oxopropyl)-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

33417-17-3

33417-17-3 structure

Name: 1-(2,3-Dihydroxy-3H-indol-3-yl)acetone
Chemical Name: 3-hydroxy-3-(2-oxopropyl)-1H-indol-2-one
CAS Number: 33417-17-3
Molecular Formula: C₁₁H₁₁NO₃
Molecular Weight: 205.210
Catalog: Natural product Alkaloid
Create Date: 2017-05-16 12:29:30
Modify Date: 2024-01-03 18:45:46
3-Acetonyl-3-hydroxyoxindole (AHO) is a potent systemic acquired resistance (SAR) inducer in plants. 3-Acetonyl-3-hydroxyoxindole induces resistance in tobacco plants against infection with tobacco mosaic virus (TMV) and the fungal pathogen Erysiphe cichoracearum. 3-Acetonyl-3-hydroxyoxindole increases the level of pathogenesis-related gene 1 (PR-1) expression, salicylic acid (SA) accumulation and phenylalanine ammonia-lyase activity[1].

Name	3-hydroxy-3-(2-oxopropyl)-1H-indol-2-one
Synonyms	3-Hydroxy-3-(2-oxopropyl)-1,3-dihydro-2H-indol-2-one 1-(2,3-Dihydroxy-3H-indol-3-yl)acetone 2H-Indol-2-one, 1,3-dihydro-3-hydroxy-3-(2-oxopropyl)- 2-propanone, 1-(2,3-dihydroxy-3H-indol-3-yl)- 3-Hydroxy-3-acetonyl-2-oxindole 3-hydroxy-3-acetonyloxindole 3-hydroxy-3-acetonylisatin

Description	3-Acetonyl-3-hydroxyoxindole (AHO) is a potent systemic acquired resistance (SAR) inducer in plants. 3-Acetonyl-3-hydroxyoxindole induces resistance in tobacco plants against infection with tobacco mosaic virus (TMV) and the fungal pathogen Erysiphe cichoracearum. 3-Acetonyl-3-hydroxyoxindole increases the level of pathogenesis-related gene 1 (PR-1) expression, salicylic acid (SA) accumulation and phenylalanine ammonia-lyase activity[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
In Vitro	3-Acetonyl-3-hydroxyoxindole (AHO) (500-700 nM) increases in endogenous SA levels and phenylalanine ammonia-lyase (PAL) activity[1]. 3-Acetonyl-3-hydroxyoxindole (0-500 nM) increases the expression of pathogenesis-related gene 1 (PR-1) in tobacco[1].
References	[1]. Li Y, et al. 3-Acetonyl-3-hydroxyoxindole: a new inducer of systemic acquired resistance in plants. Plant Biotechnol J. 2008 Apr;6(3):301-8.

Density	1.3±0.1 g/cm3
Boiling Point	450.2±45.0 °C at 760 mmHg
Melting Point	167-168℃ (Decomposition)
Molecular Formula	C₁₁H₁₁NO₃
Molecular Weight	205.210
Flash Point	226.1±28.7 °C
Exact Mass	205.073898
PSA	66.40000
LogP	0.09
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.584
Storage condition	2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NM3289480

CHEMICAL NAME :: 2H-Indol-2-one, 1,3-dihydro-3-hydroxy-3-(2-oxopropyl)-

CAS REGISTRY NUMBER :: 33417-17-3

BEILSTEIN REFERENCE NO. :: 0182807

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C11-H11-N-O3

MOLECULAR WEIGHT :: 205.23

WISWESSER LINE NOTATION :: T56 BMV DHJ DQ D1V1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 19,562,1985

Hazard Codes	Xi
HS Code	2933790090

91-56-5

67-64-1

109-77-3

~8%

33417-17-3

Detail

Literature: Kumar, Akshay; Chimni, Swapandeep Singh Beilstein Journal of Organic Chemistry, 2014 , vol. 10, p. 929 - 935

91-56-5

67-64-1

~92%

33417-17-3

Literature: Popp; Parson; Donigan Journal of Pharmaceutical Sciences, 1980 , vol. 69, # 10 p. 1235 - 1237

541-50-4

91-56-5

~93%

33417-17-3

Literature: Zhong, Fangrui; Jiang, Chunhui; Yao, Weijun; Xu, Li-Wen; Lu, Yixin Tetrahedron Letters, 2013 , vol. 54, # 32 p. 4333 - 4336

700359-40-6

~50%

33417-17-3

Literature: Kawasaki, Tomomi; Nagaoka, Miyuki; Satoh, Tomoko; Okamoto, Ayako; Ukon, Rie; Ogawa, Atsuyo Tetrahedron, 2004 , vol. 60, # 15 p. 3493 - 3503

220598-39-0

33417-17-3

Literature: Kawasaki, Tomomi; Nagaoka, Miyuki; Satoh, Tomoko; Okamoto, Ayako; Ukon, Rie; Ogawa, Atsuyo Tetrahedron, 2004 , vol. 60, # 15 p. 3493 - 3503

700359-39-3

33417-17-3

Literature: Kawasaki, Tomomi; Nagaoka, Miyuki; Satoh, Tomoko; Okamoto, Ayako; Ukon, Rie; Ogawa, Atsuyo Tetrahedron, 2004 , vol. 60, # 15 p. 3493 - 3503

91-56-5

109-89-7

67-64-1

33417-17-3

Literature: Braude; Lindwall Journal of the American Chemical Society, 1933 , vol. 55, p. 325

Precursor 8
91-56-5 67-64-1 109-77-3 541-50-4
700359-40-6 220598-39-0 700359-39-3 109-89-7
DownStream 4
91-56-5 67-64-1 634-38-8 13668-52-5

HS Code	2933790090
Summary	2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

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