3056-18-6
- Name: 9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE
- Chemical Name: [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(2,6-dichloropurin-9-yl)oxolan-2-yl]methyl acetate
- CAS Number: 3056-18-6
- Molecular Formula: C15H14Cl2N4O7
- Molecular Weight: 433.20
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2017-12-11 02:35:49
- Modify Date: 2024-01-09 12:39:03
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2,6-Dichloro-2',3',5'-triacetyl-purine riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(2,6-dichloropurin-9-yl)oxolan-2-yl]methyl acetate |
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| Synonyms | 9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE |
| Description | 2,6-Dichloro-2',3',5'-triacetyl-purine riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | |
| References |
| Density | 1.69g/cm3 |
|---|---|
| Boiling Point | 555.3ºC at 760mmHg |
| Molecular Formula | C15H14Cl2N4O7 |
| Molecular Weight | 433.20 |
| Flash Point | 289.6ºC |
| Exact Mass | 446.04000 |
| PSA | 131.73000 |
| LogP | 1.45700 |
| Index of Refraction | 1.671 |
| Hazard Codes | Xn |
|---|---|
| HS Code | 2934999090 |
|
~86%
3056-18-6 |
| Literature: Francom, Paula; Robins, Morris J. Journal of Organic Chemistry, 2003 , vol. 68, # 2 p. 666 - 669 |
|
~84%
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| Literature: Qu, Guirong; Liu, Qibin Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 1 p. 196 - 197 |
|
~75%
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| Literature: Robins; Uznanski Canadian Journal of Chemistry, 1981 , vol. 59, # 17 p. 2601 - 2607 |
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~%
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| Literature: Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 40, p. 85 - 87 |
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~%
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| Literature: Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 40, p. 85 - 87 |
|
~70%
3056-18-6 |
| Literature: Journal of Organic Chemistry, , vol. 68, # 2 p. 666 - 669 |
|
~%
3056-18-6 |
| Literature: Canadian Journal of Chemistry, , vol. 59, # 17 p. 2601 - 2607 |
|
~%
3056-18-6 |
| Literature: Canadian Journal of Chemistry, , vol. 59, # 17 p. 2601 - 2607 |
|
~%
3056-18-6 |
| Literature: Canadian Journal of Chemistry, , vol. 59, # 17 p. 2601 - 2607 |
| Precursor 9 | |
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| DownStream 5 | |
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |