Top Suppliers:I want be here
  • BioBioPha
  • China
  • Product Name: Isopimpinellin
  • Price: ￥Inquiry/20mg
  • Purity: 98.0%
  • Stocking Period: 1 Day
  • Contact: Xueping-Zheng
Hot CAS#:
56-41-7 108-65-6
56-35-9 64-17-5
67-56-1 108-88-3
141-78-6 1310-73-2
13463-67-7 1333-86-4

482-27-9

482-27-9 structure
482-27-9 structure
  • Name: Isopimpinellin
  • Chemical Name: isopimpinellin
  • CAS Number: 482-27-9
  • Molecular Formula: C13H10O5
  • Molecular Weight: 246.215
  • Catalog: Pharmaceutical intermediate Heterocyclic compound Pyran compound
  • Create Date: 2018-09-09 10:20:58
  • Modify Date: 2024-01-02 11:54:52
  • Isopimpinellin, an orally active compound isolated from the roots of Pimpinella saxifrage. Isopimpinellin blocks DNA adduct formation and skin tumor initiation by 7,12-dimethylbenz[a]anthracene. Isopimpinellin possesses anti-leishmania effect[1].
Name isopimpinellin
Synonyms 5,8-Dimethoxypsoralen
4,9-Dimethoxy-furo[3,2-g]chromen-7-one
4,9-Dimethoxyfuro[3,2-g]benzopyran-7-one
4,9-Dimethoxy-7H-furo[3,2-g][1]benzopyran-7-one
4,9-dimethoxyfuro[3,2-g]chromen-7-one
4,9-Dimethoxy-7H-furo[3,2-g]chromen-7-one
MFCD00017407
7H-Furo[3,2-g][1]benzopyran-7-one, 4,9-dimethoxy-
Isopimpinellin
Description Isopimpinellin, an orally active compound isolated from the roots of Pimpinella saxifrage. Isopimpinellin blocks DNA adduct formation and skin tumor initiation by 7,12-dimethylbenz[a]anthracene. Isopimpinellin possesses anti-leishmania effect[1].
Related Catalog
In Vivo Isopimpinellin (oral gavage, 35-150 mg/kg) inhibits B[a]P-DNA adduct formation and DMBA–DNA adduct formation in SENCAR mice with skin tumor[1]. Animal Model: Female SENCAR mice (7-9 weeks of age) were fed AIN-76A semi-purified diet (Dyets, Bethlehem, PA) for 2 weeks prior to and during the study[1]. Dosage: 35–150 mg/kg. Administration: Oral gavage, suspended in 0.1 mL corn oil at 24 h and 2 h prior to topical treatment with [3H]B[a]P (200 nmol, 1 Ci/mmol) or [3H]DMBA (10 nmol, 10 Ci/mmol) (each in 0.2 mL acetone). Result: Significantly inhibited B[a]P-DNA adduct formation by 37 and 26%, respectively. Isopimpinellin (35, 70 and 150 mg/kg) blocked DMBA–DNA adduct formation by 23, 56 and 69%, respectively
References

[1]. Kleiner HE, et al. Oral administration of the citrus coumarin, isopimpinellin, blocks DNA adduct formation and skin tumor initiation by 7,12-dimethylbenz[a]anthracene in SENCAR mice. Carcinogenesis. 2002 Oct;23(10):1667-75.
Density 1.4±0.1 g/cm3
Boiling Point 448.7±45.0 °C at 760 mmHg
Melting Point 150-151ºC
Molecular Formula C13H10O5
Molecular Weight 246.215
Flash Point 225.1±28.7 °C
Exact Mass 246.052826
PSA 61.81000
LogP 2.31
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.612
Storage condition 2-8°C
Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H300
Precautionary Statements P264-P301 + P310
Hazard Codes T+
Risk Phrases 20/21/22
Safety Phrases 22-36/37/39-45-36/37-28
RIDADR UN 2811 6.1 / PGII
RTECS LV1049200
14348-23-3 structure

14348-23-3
74-88-4 structure

74-88-4

~80%

482-27-9 structure

482-27-9
Literature: Bioorganic and Medicinal Chemistry, , vol. 20, # 2 p. 784 - 788
298-81-7 structure

298-81-7

~%

482-27-9 structure

482-27-9
Literature: Journal of Organic Chemistry, , vol. 24, p. 523,525
483-36-3 structure

483-36-3

~%

482-27-9 structure

482-27-9
Literature: Journal of Organic Chemistry, , vol. 24, p. 523,525
186581-53-3 structure

186581-53-3
1603-47-0 structure

1603-47-0

~%

482-27-9 structure

482-27-9
Literature: Journal of the Chemical Society, , p. 4163,4168 Chemische Berichte, , vol. 71, p. 344,351 Yakugaku Zasshi, , vol. 58, p. 370,377 Monatshefte fuer Chemie, , vol. 72, p. 179,187 Yakugaku Zasshi, , vol. 60, p. 57,61 Chem.Abstr., , p. 3717
14348-23-3 structure

14348-23-3
77-78-1 structure

77-78-1

~%

482-27-9 structure

482-27-9
Literature: Journal of Organic Chemistry, , vol. 24, p. 523,525
186581-53-3 structure

186581-53-3
14348-23-3 structure

14348-23-3

~%

482-27-9 structure

482-27-9
Literature: Monatshefte fuer Chemie, , vol. 59, p. 161,170
1603-47-0 structure

1603-47-0
74-88-4 structure

74-88-4

~%

482-27-9 structure

482-27-9
Literature: Journal of the Indian Chemical Society, , vol. 25, p. 139,141

Chemsrc provides CAS#:482-27-9 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 482-27-9 | Chemsrc address: https://www.chemsrc.com/en/baike/899288.html

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved