Bioorganic & medicinal chemistry

Structure–activity relationships for naturally occurring coumarins as β-secretase inhibitor

S Marumoto, M Miyazawa

Index: Bioorganic and Medicinal Chemistry, , vol. 20, # 2 p. 784 - 788

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Citation Number: 18

Abstract

... Bioorganic & Medicinal Chemistry. ... 4. Alzheimer's disease (AD) has become an increasingly severe medical and social problem, due to the rapid growth of aging ... Otherwise, in previous studies, furanocoumarins from medicinal plant A. dahurica showed inhibition effects of BACE1 ...