Top Suppliers:I want be here
Related CAS#:
77-09-8 5768-87-6
2037-19-6 25296-54-2
6607-41-6 52404-53-2
6607-42-7 8053-05-2
29717-26-8 62698-58-2
921853-27-2 921853-31-8
921806-75-9 921806-78-2
921539-61-9 921807-59-2
921578-00-9 921578-37-2
921807-75-2 921854-78-6

77-09-8

77-09-8 structure
77-09-8 structure
Name Phenolphthalein
Synonyms Evac-U-Gen
a-(p-Hydroxyphenyl)-a-(4-oxo-2,5-cyclohexadien-1-ylidine)-o-toluic Acid
Phenolphthalein
White phenolphthalein
Evac-Q-Kit
Ex-Lax
Evac-Q-Tabs
MFCD00005913
Chocolax
EINECS 201-004-7
Evac-Q-Kwik
3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofurunone
1(3H)-Isobenzofuranone, 3,3-bis(4-hydroxyphenyl)-
5-18-04-00188 (Beilstein Handbook Reference)
Colax
Purgophen (VAN)
Feen-A-Mint Laxative Mints
3,3-bis(4-hydroxyphenyl)-2-benzofuran-1-one
3,3-Bis(4-hydroxyphenyl)-2-benzofuran-1(3H)-one
Evac-V-Lax
Density 1.4±0.1 g/cm3
Boiling Point 557.8±50.0 °C at 760 mmHg
Melting Point 258-263 °C
Molecular Formula C20H14O4
Molecular Weight 318.323
Flash Point 206.5±23.6 °C
Exact Mass 318.089203
PSA 66.76000
LogP 2.63
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.693
Stability Stable. Incompatible with strong oxidizing agents, alkalies.
Water Solubility <0.1 g/100 mL

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SM8380000
CHEMICAL NAME :
Phenolphthalein
CAS REGISTRY NUMBER :
77-09-8
BEILSTEIN REFERENCE NO. :
0284423
LAST UPDATED :
199803
DATA ITEMS CITED :
20
MOLECULAR FORMULA :
C20-H14-O4
MOLECULAR WEIGHT :
318.34
WISWESSER LINE NOTATION :
T56 BVO DHJ D- D-/R DQ 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
29 mg/kg
TOXIC EFFECTS :
Gastrointestinal - gastritis Gastrointestinal - nausea or vomiting Kidney, Ureter, Bladder - other changes in urine composition
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
324 gm/kg/13W-C
TOXIC EFFECTS :
Liver - changes in liver weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
106 gm/kg/13W-C
TOXIC EFFECTS :
Liver - changes in liver weight Blood - changes in erythrocyte (RBC) count Related to Chronic Data - changes in testicular weight
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
364 gm/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors Endocrine - adrenal cortex tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
281 gm/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Endocrine - tumors Skin and Appendages - tumors
TYPE OF TEST :
Micronucleus test

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
50 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 341,151,1995 *** REVIEWS *** TOXICOLOGY REVIEW DAPOAG Deutsche Apotheker. (Postfach 1650, 6370 Oberusel/Taunas, Fed. Rep. Ger.) V.1- 1949- Volume(issue)/page/year: 27,151,1975 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0011 No. of Facilities: 8 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 31 (estimated) NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 56240 No. of Facilities: 6160 (estimated) No. of Industries: 102 No. of Occupations: 43 No. of Employees: 43092 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9187 No. of Facilities: 117 (estimated) No. of Industries: 3 No. of Occupations: 6 No. of Employees: 1946 (estimated) No. of Female Employees: 1408 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 56240 No. of Facilities: 6900 (estimated) No. of Industries: 89 No. of Occupations: 57 No. of Employees: 73297 (estimated) No. of Female Employees: 18309 (estimated)
Symbol GHS02 GHS07 GHS08
GHS02, GHS07, GHS08
Signal Word Danger
Hazard Statements H225-H319-H341-H350
Precautionary Statements P201-P210-P280-P308 + P313-P337 + P313-P403 + P235
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn:Harmful
Risk Phrases R22;R40
Safety Phrases S45-S36/37-S33-S24-S16-S7
RIDADR UN 1993
RTECS SM8380000
Hazard Class 3.0
HS Code 29322910
85-44-9 structure

85-44-9

108-95-2 structure

108-95-2

~96%

77-09-8 structure

77-09-8

Literature: Sabnis, Ram W. Tetrahedron Letters, 2009 , vol. 50, # 46 p. 6261 - 6263
85-57-4 structure

85-57-4

108-95-2 structure

108-95-2

~%

77-09-8 structure

77-09-8

Literature: Ghatak Bl. Acad. Sci. Agra Oudh, 1933 , vol. 2, p. 253,255
85-44-9 structure

85-44-9

108-95-2 structure

108-95-2

~%

77-09-8 structure

77-09-8

596-24-7 structure

596-24-7

Literature: Baeyer Justus Liebigs Annalen der Chemie, 1882 , vol. 212, p. 349 Full Text Show Details Meyer,R. Chemische Berichte, 1891 , vol. 24, p. 1414,2600 Chemische Berichte, 1893 , vol. 26, p. 205 Full Text Show Details Baeyer Chemische Berichte, 1871 , vol. 4, p. 659 Chemische Berichte, 1876 , vol. 9, p. 1233 Full Text Show Details Baeyer Justus Liebigs Annalen der Chemie, 1880 , vol. 202, p. 56,63
62625-15-4 structure

62625-15-4

~%

77-09-8 structure

77-09-8

Literature: Nishizawa, Masako; Yabusaki, Yoshiyasu; Kanaoka, Masaharu Bioscience, Biotechnology and Biochemistry, 2011 , vol. 75, # 1 p. 89 - 94
88-99-3 structure

88-99-3

108-95-2 structure

108-95-2

~%

77-09-8 structure

77-09-8

Literature: Copisarow Journal of the Chemical Society, 1920 , vol. 117, p. 215
509-77-3 structure

509-77-3

~%

77-09-8 structure

77-09-8

Literature: Baeyer Chemische Berichte, 1879 , vol. 12, p. 644 Justus Liebigs Annalen der Chemie, 1880 , vol. 202, p. 52
84755-69-1 structure

84755-69-1

~%

77-09-8 structure

77-09-8

Literature: Yamaguchi; Mori; Suketa Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 1 p. 159 - 163
HS Code 29322910
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Chemsrc provides CAS#:77-09-8 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 77-09-8 | Chemsrc address: https://www.chemsrc.com/en/baike/895872.html

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved