Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1-[3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]-5-fluoro-pyrimidine-2,4-dione
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Purity: 98.0%
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56527-42-5

56527-42-5 structure

Name: 1-[3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]-5-fluoro-pyrimidine-2,4-dione
Chemical Name: 1-[3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]-5-fluoropyrimidine-2,4-dione
CAS Number: 56527-42-5
Molecular Formula: C₉H₁₁FN₂O₅S
Molecular Weight: 278.26
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2016-10-01 00:42:10
Modify Date: 2024-01-14 21:20:57
5-Fluoro-4’-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1-[3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]-5-fluoropyrimidine-2,4-dione
Synonyms	Uridine,5-fluoro-4'-thio 5-fluoro-4-thio-uridine

Description	5-Fluoro-4’-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.