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Related CAS#:
503-49-1 638-18-6
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503-49-1

503-49-1 structure
503-49-1 structure
  • Name: 3-hydroxy-3-methylglutaric acid
  • Chemical Name: 3-hydroxy-3-methylglutaric acid
  • CAS Number: 503-49-1
  • Molecular Formula: C6H10O5
  • Molecular Weight: 162.14100
  • Catalog: Biochemical Amino acids and their derivatives Glutamic acid derivative
  • Create Date: 2018-04-10 08:00:00
  • Modify Date: 2024-01-03 07:59:53
  • Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids, and inhibits the activity of hydroxymethylglutarryl CoA reductases, which is the rate limiting enzyme in the biosynthesis of cholesterol.
Name 3-hydroxy-3-methylglutaric acid
Synonyms EINECS 207-971-1
MFCD00002712
3-hydroxy-3-methylpentanedioic acid
3-Hydroxy-3-Methylglutaric Acid
Meglutol
Description Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids, and inhibits the activity of hydroxymethylglutarryl CoA reductases, which is the rate limiting enzyme in the biosynthesis of cholesterol.
Related Catalog
Density 1.417 g/cm3
Boiling Point 120 °C / 13mmHg
Melting Point 105-108 °C(lit.)
Molecular Formula C6H10O5
Molecular Weight 162.14100
Flash Point 182.2ºC
Exact Mass 162.05300
PSA 94.83000
Index of Refraction 1.512
Storage condition −20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MA3753000
CHEMICAL NAME :
Glutaric acid, 3-hydroxy-3-methyl-
CAS REGISTRY NUMBER :
503-49-1
BEILSTEIN REFERENCE NO. :
1769194
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C6-H10-O5
MOLECULAR WEIGHT :
162.16
WISWESSER LINE NOTATION :
QV1XQ1&1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
7330 mg/kg
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 25,1284,1975
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3230 mg/kg
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 25,1284,1975
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS MA3753000
HS Code 2918199090
HS Code 2918199090
Summary 2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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