674-26-0

674-26-0 structure

Name: DL-Mevalonolactone
Chemical Name: DL-Mevalonolactone
CAS Number: 674-26-0
Molecular Formula: C₆H₁₀O₃
Molecular Weight: 130.14200
Catalog: Chemical reagent Organic reagent Ester Lactone compound
Create Date: 2018-08-21 11:14:39
Modify Date: 2024-01-01 19:28:44
DL-Mevalonolactone ((±)-Mevalonolactone;Mevalolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone (Mevalonolactone) decreases mitochondrial membrane potential (∆Ψm), NAD(P)H content and the capacity to retain Ca2+ in the brain, besides inducing mitochondrial swelling[1][2].

Name	DL-Mevalonolactone
Synonyms	(3RS)-mevalonolactone MEVALONIC LACTONE (+/-)-MEVALONOLACTONE EINECS 211-615-0 DL-MEVALOLACTONE MFCD00006648 DL-mevalonic acid lactone D,L-MEVELONIC ACID LACTONE MEVALONIC ACID LACTONE,DL (RS)-mevalonolactone (S/R)-mevalonolactone

Description	DL-Mevalonolactone ((±)-Mevalonolactone;Mevalolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone (Mevalonolactone) decreases mitochondrial membrane potential (∆Ψm), NAD(P)H content and the capacity to retain Ca2+ in the brain, besides inducing mitochondrial swelling[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Domingos SR, et al. On the structural intricacies of a metabolic precursor: Direct spectroscopic detection of water-induced conformational reshaping of mevalonolactone. J Chem Phys. 2017 Sep 28;147(12):124310. [2]. Cecatto C, et al. Mevalonolactone disrupts mitochondrial functions and induces permeability transition pore opening in rat brain mitochondria: Implications for the pathogenesis of mevalonic aciduria. Neurochem Int. 2017 Sep;108:133-145.

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RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2932999099

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%