55096-26-9
55096-26-9 structure
- Name: Nalmefene
- Chemical Name: (4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylidene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol
- CAS Number: 55096-26-9
- Molecular Formula: C21H25NO3
- Molecular Weight: 339.43
- Catalog: Signaling Pathways GPCR/G Protein Opioid Receptor
- Create Date: 2018-09-18 16:22:43
- Modify Date: 2025-08-21 11:09:27
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Nalmefene is a long acting opioid (MOR and DOR antagonist), and a partial KOR agonist. Nalmefene is used for opioid overdose and alcohol dependence[1].
| Name | (4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylidene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol |
|---|---|
| Synonyms |
Arthene
Nalmefenum Nalmetrenum Alcofene Nalmetreno 6-desoxy-6-methylenenaltrexone Nalmetrene Revex nalmefene Cervene |
| Description | Nalmefene is a long acting opioid (MOR and DOR antagonist), and a partial KOR agonist. Nalmefene is used for opioid overdose and alcohol dependence[1]. |
|---|---|
| Related Catalog | |
| Target |
MOR, DOR, KOR[1] |
| References |
| Melting Point | 188 - 190ºC |
|---|---|
| Molecular Formula | C21H25NO3 |
| Molecular Weight | 339.43 |
| Exact Mass | 339.18300 |
| PSA | 52.93000 |
| LogP | 2.45040 |
| Storage condition | 2-8°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
|
~%
55096-26-9 |
| Literature: Synthetic Communications, , vol. 22, # 16 p. 2313 - 2327 |
|
~%
55096-26-9 |
| Literature: Journal of Medicinal Chemistry, , vol. 18, p. 259 - 262 |
| Precursor 3 | |
|---|---|
| DownStream 0 | |