66548-69-4
66548-69-4 structure
- Name: CL 218872
- Chemical Name: 3-methyl-6-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine
- CAS Number: 66548-69-4
- Molecular Formula: C13H9F3N4
- Molecular Weight: 278.23300
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel GABA Receptor
- Create Date: 2018-12-25 08:36:39
- Modify Date: 2024-01-17 13:00:56
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CL 218872 is a selective and orally active benzodiazepine of α1 subunit-containing GABAAreceptor with a Ki of 130 nM. CL 218872 exerts anxiolytic and anticonvulsant in vivo[1].
| Name | 3-methyl-6-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine |
|---|---|
| Synonyms |
CL 218,872
Tocris-1709 |
| Description | CL 218872 is a selective and orally active benzodiazepine of α1 subunit-containing GABAAreceptor with a Ki of 130 nM. CL 218872 exerts anxiolytic and anticonvulsant in vivo[1]. |
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| Related Catalog | |
| References |
| Density | 1.43g/cm3 |
|---|---|
| Molecular Formula | C13H9F3N4 |
| Molecular Weight | 278.23300 |
| Exact Mass | 278.07800 |
| PSA | 43.08000 |
| LogP | 3.11850 |
| Index of Refraction | 1.615 |
| Storage condition | -20°C |
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66548-69-4 |
| Literature: American Cyanamid Company Patent: US4112095 A1, 1978 ; |
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66548-69-4 |
| Literature: Lieberman, Daniel F.; Albright, J. Donald Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 827 - 830 |
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66548-69-4 |
| Literature: Albright, J. D.; Moran, D. B.; Wright, W. B.; Collins, J. B.; Beer, B.; et al. Journal of Medicinal Chemistry, 1981 , vol. 24, # 5 p. 592 - 600 |
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66548-69-4 |
| Literature: Lieberman, Daniel F.; Albright, J. Donald Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 827 - 830 |
|
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66548-69-4 |
| Literature: Lieberman, Daniel F.; Albright, J. Donald Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 827 - 830 |
| Precursor 6 | |
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| DownStream 0 | |