87-17-2

87-17-2 structure

Name: Salicylanilide
Chemical Name: salicylanilide
CAS Number: 87-17-2
Molecular Formula: C₁₃H₁₁NO₂
Molecular Weight: 213.232
Catalog: API Synthetic anti-infective drugs Disinfectant antiseptic
Create Date: 2018-09-02 14:02:26
Modify Date: 2024-01-02 13:29:46
Salicylanilide demonstrates a wide range of biological activities including antiviral potency which can inhibit HIV virus by targeting HIV-1 integrase or reverse transcriptase.

Name	salicylanilide
Synonyms	2-Phenylaminocarbonylphenol Salinide Benzamide, 2-hydroxy-N-phenyl- Salicylanilid 2-Hydroxy-N-phenylbenzamide Salifebrin Ansadol salicylamide salicylic acid anilide N-Phenylsalicylamide Hyanilid EINECS 201-727-8 2-hydroxy-N-phenyl-benzamide Aseptolan Salicylanilide MFCD00002212

Description	Salicylanilide demonstrates a wide range of biological activities including antiviral potency which can inhibit HIV virus by targeting HIV-1 integrase or reverse transcriptase.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> HIV Integrase Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
Target	HIV-1 integrase, reverse transcriptase[1]
In Vitro	Some Salicylanilides and salicylamides could inhibit HIV virus by targeting of HIV-1 integrase or reverse transcriptase. Hepatitis C virus is another virus, which can be potentially afflicted by Salicylanilides on the level of two enzymes-NS3 protease and NS5B RNA polymerase[1].
References	[1]. Krátký M, et al. Antiviral activity of substituted salicylanilides--a review. Mini Rev Med Chem. 2011 Oct;11(11):956-67.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,663,1986

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 44,465,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82917 No. of Facilities: 178 (estimated) No. of Industries: 7 No. of Occupations: 5 No. of Employees: 837 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82917 No. of Facilities: 637 (estimated) No. of Industries: 10 No. of Occupations: 14 No. of Employees: 27279 (estimated) No. of Female Employees: 21161 (estimated)

Symbol	GHS07, GHS09
Signal Word	Warning
Hazard Statements	H315-H319-H335-H400
Precautionary Statements	P261-P273-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S37/39
RIDADR	UN 3077 9 / PGIII
WGK Germany	2
RTECS	VN7850000
HS Code	29242995

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%