Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: PHENIPRAZINE HYDROCHLORIDE
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Purity: 98.0%
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66-05-7

66-05-7 structure

66-05-7 structure

Name: PHENIPRAZINE HYDROCHLORIDE
Chemical Name: 1-phenylpropan-2-ylhydrazine,hydrochloride
CAS Number: 66-05-7
Molecular Formula: C₉H₁₅ClN₂
Molecular Weight: 186.68200
Catalog: Signaling Pathways Neuronal Signaling Monoamine Oxidase
Create Date: 2016-08-24 15:45:53
Modify Date: 2024-01-14 22:11:21
Pheniprazine hydrochloride is a potent and long acting inhibitor of monoamine oxidase. Pheniprazine has the potential for the research of depression[1].

Name	1-phenylpropan-2-ylhydrazine,hydrochloride

Description	Pheniprazine hydrochloride is a potent and long acting inhibitor of monoamine oxidase. Pheniprazine has the potential for the research of depression[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease
References	[1]. HORITA A. beta-Phenylisopropylhydrazine, a potent and long acting monoamine oxidase inhibitor. J Pharmacol Exp Ther. [2]. Stein, Larry, et al. Accelerated recovery from reserpine depression by monoamine oxidase inhibitors.

Molecular Formula	C₉H₁₅ClN₂
Molecular Weight	186.68200
Exact Mass	186.09200
PSA	38.05000
LogP	2.97410

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MV7400000

CHEMICAL NAME :: Hydrazine, (alpha-methylphenethyl)-, monohydrochloride

CAS REGISTRY NUMBER :: 66-05-7

LAST UPDATED :: 199206

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C9-H14-N2.Cl-H

MOLECULAR WEIGHT :: 186.71

WISWESSER LINE NOTATION :: ZM1Y1&R &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 18,617,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 59 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IJNEAQ International Journal of Neuropharmacology. (New York, NY) V.1-8, 1962-69. For publisher information, see NEPHBW. Volume(issue)/page/year: 5,125,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 112 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay)

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 18,20,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 87 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IJNEAQ International Journal of Neuropharmacology. (New York, NY) V.1-8, 1962-69. For publisher information, see NEPHBW. Volume(issue)/page/year: 5,125,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 66 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IJNEAQ International Journal of Neuropharmacology. (New York, NY) V.1-8, 1962-69. For publisher information, see NEPHBW. Volume(issue)/page/year: 5,125,1966