Name | le 300 |
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Synonyms |
Tocris-1674
Lopac-L-8401 |
Description | LE 300 is a potent and selective dopamine D1-like receptor antagonist with Kis of 1.9 nM and 7.5 nM in CHO cell membranes expressing human dopamine D1 and D5 receptors, respectively. LE 300 is an antagonist of the 5-HT2A receptor with a pA2 of 8.32 in a rat tail artery assay[1][2]. |
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Related Catalog | |
Target |
Human D1 Receptor:1.9 nM (Ki) Human D5 Receptor:7.5 nM (Ki) Rat 5-HT2A:8.32 (pA2) |
References |
Density | 1.114g/cm3 |
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Boiling Point | 464ºC at 760 mmHg |
Molecular Formula | C20H22N2 |
Molecular Weight | 290.40200 |
Flash Point | 234.4ºC |
Exact Mass | 290.17800 |
PSA | 19.03000 |
LogP | 3.72700 |
Vapour Pressure | 8.69E-09mmHg at 25°C |
Index of Refraction | 1.63 |