Shanghai Nianxing Industrial Co., Ltd
China
Product Name: H-D-Glu(Gly-OH)-OH
Price: Check
Purity: 99.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

GL Biochem (Shanghai) Ltd.
China
Product Name: H-D-Glu(Gly-OH)-OH
Price: $Inquiry/1kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Jackie Yang
Email: ymbetter@glbiochem.com

DC Chemicals Limited
China
Product Name: gammaDGG
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: gammaDGG
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

Nanjing Peptide Biotech Ltd
China
Product Name: H-D-Glu(Gly-OH)-OH
Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
Purity: 98.0%
Stocking Period: 7 Day
Contact: jom
Email: chenglong.fan@njpeptide.com

6729-55-1

6729-55-1 structure

6729-55-1 structure

Name: H-D-Glu(Gly-OH)-OH
Chemical Name: γ-D-Glutamylglycine
CAS Number: 6729-55-1
Molecular Formula: C₇H₁₂N₂O₅
Molecular Weight: 204.18100
Catalog: Biochemical Amino acids and their derivatives Glycine derivatives
Create Date: 2018-05-15 08:00:00
Modify Date: 2024-01-02 12:58:58
gamma-DGG is a competitive AMPA receptor blocker.

Name	γ-D-Glutamylglycine
Synonyms	D-g-Glutamylglycine H-D-Glu(Gly-OH)-OH gamma-DGG

Description	gamma-DGG is a competitive AMPA receptor blocker.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease
Target	AMPA receptor[1]
In Vitro	gamma-DGG (γ-DGG), a competitive AMPA receptor blocker that blocks less at higher glutamate concentration. At 200-400 μM, gamma-DGG in the bath reduces the miniature EPSC (mEPSC) amplitude by 26±2% (n=5 synapses), and shifts both the mEPSC amplitude distribution and the cumulative probability curve to the left[1]. gamma-DGG (γ-DGG) is the most effective antagonist of the excitatory post-synaptic potentials (e.p.s.p.s). Its action is reversible and not associated with any change in the passive membrane properties of the granule cells or in the apparent reversal potential of the e.p.s.p. Quantal analysis shows that the reduction in the e.p.s.p. paralleled the decrease in quantal size rather than quantal content, confirming a post-synaptic site of the action of gamma-DGG[2].
References	[1]. Wu XS, et al. The origin of quantal size variation: vesicular glutamate concentration plays a significant role. J Neurosci. 2007 Mar 14;27(11):3046-56. [2]. Crunelli V, et al. Blockade of amino acid-induced depolarizations and inhibition of excitatory post-synaptic potentials in rat dentate gyrus. J Physiol. 1983 Aug;341:627-40.

Boiling Point	586.6ºC at 760 mmHg
Molecular Formula	C₇H₁₂N₂O₅
Molecular Weight	204.18100
Flash Point	308.6ºC
Exact Mass	204.07500
PSA	129.72000
Storage condition	-15°C

HS Code	2924199090

HS Code	2924199090
Summary	2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%