2199-87-3

2199-87-3 structure

Name: 6-bromocoumarin-3-carboxylic acid
Chemical Name: 6-bromo-2-oxochromene-3-carboxylic acid
CAS Number: 2199-87-3
Molecular Formula: C₁₀H₅BrO₄
Molecular Weight: 269.04800
Catalog: Pharmaceutical intermediate Heterocyclic compound Pyran compound
Create Date: 2018-09-06 23:05:33
Modify Date: 2025-08-25 19:58:14
UBP608 is a potent N-Methyl-D-aspartate receptors (NMDARs) negative allosteric modulator. UBP608 has the potential for the research of neurological disorders[1].

Name	6-bromo-2-oxochromene-3-carboxylic acid
Synonyms	6-bromo-2-oxo-2H-1-benzopyran-3-carboxylic acid 6-Bromochromon-3-carboxylic acid 6-Bromo-2-oxo-2H-chromene-3-carboxylic acid 6-Bromo-3-carboxycoumarin 6-bromo-2-oxo-2Hchromene-3-carboxylic acid MFCD00047640 6-Bromocoumarin-3-carboxylic acid 6-Bromocoumarin-3-carboxylicAcid

Description	UBP608 is a potent N-Methyl-D-aspartate receptors (NMDARs) negative allosteric modulator. UBP608 has the potential for the research of neurological disorders[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
Target	NMDA Receptor
In Vitro	UBP608 (100 µM) 显示出抑制活性，对 GluN1/GluN2A、GluN1/GluN2B、GluN1/GluN2C、GluN1/GluN2D 的抑制率分别为 89.3%、63.5%、56.1%、23.6%[1]。
References	[1]. Irvine MW, et al. Coumarin-3-carboxylic acid derivatives as potentiators and inhibitors of recombinant and native N-methyl-D-aspartate receptors. Neurochem Int. 2012 Sep;61(4):593-600.

Hazard Codes	Xi: Irritant;
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2932209090

HS Code	2932209090
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%