DC Chemicals Limited
China
Product Name: Pirenperone
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: PIRENPERONE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

75444-65-4

75444-65-4 structure

75444-65-4 structure

Name: Pirenperone
Chemical Name: 3-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-2-methylpyrido[1,2-a]pyrimidin-4-one
CAS Number: 75444-65-4
Molecular Formula: C₂₃H₂₄FN₃O₂
Molecular Weight: 393.45
Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
Create Date: 2018-09-29 00:00:32
Modify Date: 2024-01-06 02:45:41
Pirenperone (R 47465) is a 5-HT2 serotonin receptor antagonist. Pirenperone exhibits modest anxiolytic activity[1][2].

Name	3-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-2-methylpyrido[1,2-a]pyrimidin-4-one
Synonyms	4H-Pyrido(1,2-a)pyrimidin-4-one,3-(2-(4-(4-fluorobenzoyl)-1-piperidinyl)ethyl)-2-methyl 3-<2-(4-(4-fluorobenzoyl)piperidino)-ethyl>-2-methyl-4H-pyrido<1,2-a>-pyrimidin-4-one 1-[2-(2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)ethyl]-4-(4-fluorobenzoyl)piperidine Pirenperone EINECS 278-213-5 Pirenperona [INN-Spanish] Pirenperonum [INN-Latin] R-47,465 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]-ethyl]-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Description	Pirenperone (R 47465) is a 5-HT2 serotonin receptor antagonist. Pirenperone exhibits modest anxiolytic activity[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
References	[1]. Krstić MK, et, al. Divergent effects of pirenperone, a 5-HT2 antagonist, on the pressor and tachycardic responses to 5-HT in guinea-pigs. Arch Int Physiol Biochim. 1983 Nov;91(4):345-9. [2]. Ansseau M, et, al. Pilot study of a specific serotonergic antagonist, pirenperone, in the treatment of anxiety disorders. Acta Psychiatr Belg. Sep-Oct 1983;83(5):517-24.

Density	1.26g/cm3
Boiling Point	556.3ºC at 760 mmHg
Molecular Formula	C₂₃H₂₄FN₃O₂
Molecular Weight	393.45
Flash Point	290.2ºC
Exact Mass	393.18500
PSA	54.68000
LogP	3.21730
Index of Refraction	1.629

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
RIDADR	NONH for all modes of transport
WGK Germany	3

67-66-3 structure

67-66-3

25519-78-2 structure

25519-78-2

108-10-1 structure

108-10-1

41078-70-0 structure

41078-70-0

~%

Detail

Literature: Janssen Pharmaceutica N.V. Patent: US4342870 A1, 1982 ;

Precursor 4
67-66-3 25519-78-2 108-10-1 41078-70-0
DownStream 0