67600-94-6

67600-94-6 structure

Name: Hydrangel 8-O-glucoside
Chemical Name: 3-(4-Hydroxyphenyl)-1-oxo-3,4-dihydro-1H-isochromen-8-yl β-D-gluc opyranoside
CAS Number: 67600-94-6
Molecular Formula: C₂₁H₂₂O₉
Molecular Weight: 418.39
Catalog: Natural product Coumarin
Create Date: 2017-08-23 13:21:05
Modify Date: 2025-08-28 09:01:14
Hydrangenol 8-O-glucoside (Hydrangenol 8-O-β-D-glucopyranoside) can be isolated from Hydrangea macrophyllu. Hydrangenol 8-O-glucoside is an AChE inhibitor (IC50: 22.66 μM). Hydrangenol 8-O-glucoside inhibits passive cutaneous anaphylaxis (PCA) reaction[1][2].

Name	3-(4-Hydroxyphenyl)-1-oxo-3,4-dihydro-1H-isochromen-8-yl β-D-gluc opyranoside
Synonyms	1H-2-Benzopyran-1-one, 8-(β-D-glucopyranosyloxy)-3,4-dihydro-3-(4-hydroxyphenyl)- 3-(4-Hydroxyphenyl)-1-oxo-3,4-dihydro-1H-isochromen-8-yl β-D-glucopyranoside

Description	Hydrangenol 8-O-glucoside (Hydrangenol 8-O-β-D-glucopyranoside) can be isolated from Hydrangea macrophyllu. Hydrangenol 8-O-glucoside is an AChE inhibitor (IC50: 22.66 μM). Hydrangenol 8-O-glucoside inhibits passive cutaneous anaphylaxis (PCA) reaction[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
References	[1]. Matsuda H, et al. Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and thunberginols A and F from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats. Biol Pharm Bull. 1999 Aug;22(8):870-2. [2]. Hwang J, et al. Discovery of Natural Inhibitors of Cholinesterases from Hydrangea: In Vitro and In Silico Approaches. Nutrients. 2021 Jan 17;13(1):254.

Hazard Codes	Xi

Precursor 0
DownStream 1
480-47-7