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549-21-3

549-21-3 structure
549-21-3 structure
  • Name: 8-Oxyberberine
  • Chemical Name: Oxyberberine
  • CAS Number: 549-21-3
  • Molecular Formula: C20H17NO5
  • Molecular Weight: 351.353
  • Catalog: Research Areas Others
  • Create Date: 2018-03-11 08:00:00
  • Modify Date: 2025-08-21 17:09:11
  • Berlambine is a natural alkaloid isolated from many plants[1].

Name Oxyberberine
Synonyms 8H-1,3-Benzodioxolo[5,6-a]benzo[g]quinolizin-8-one, 5,6-dihydro-9,10-dimethoxy-
8-oxoberberine
9,10-Dimethoxy-5,6-dihydro-8H-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-8-one
9,10-Dimethoxy-5,6-dihydro-8H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-8-one
Ketoberberine
berberin-8-one
Berlambine
Density 1.4±0.1 g/cm3
Boiling Point 611.5±55.0 °C at 760 mmHg
Melting Point 200-201ºC
Molecular Formula C20H17NO5
Molecular Weight 351.353
Flash Point 323.6±31.5 °C
Exact Mass 351.110687
PSA 58.92000
LogP 3.87
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.691
Water Solubility Insuluble (1.8E-3 g/L) (25 ºC)

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DS0180000
CHEMICAL NAME :
8-Berbinone, 13,13a-didehydro-9,10-dimethoxy-2,3-(methylenedioxy)-
CAS REGISTRY NUMBER :
549-21-3
BEILSTEIN REFERENCE NO. :
0339209
LAST UPDATED :
199709
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H17-N-O5
MOLECULAR WEIGHT :
351.38
WISWESSER LINE NOTATION :
T G5 D6 C666 HO JO ONV IH&&T&&J RO1 SO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
240 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 15,486,1981
Hazard Codes Xi
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